Behavioural Approaches To Neuroscience 2 Flashcards
Neural imaging- structural measures
Skull XR Cerebral angiography Computed tomography Magnetic resonance imaging Pneumoencephalography
MRI
Takes sections through brain
Magnetic field aligns H atoms, radio waves cause them to spin producing a signal
Voxel based morphemetry-> used to calculate the size of an area
Diffusion MRI-> diffusion of water molecules-> movement restricted once in a nerve-> map white matter tracts
Measure cortisol thickness -> thinner in Tourette’s
Neuroimaging functional measures
Positron emission tomography
Functional MRI
Single proton emission tomography
fMRI
Measures brain activity in the living brain
Measures change in cerebral blood flow during cognitive tasks-> increased doxyhaemaglobin in active areas
BOLD-> blood oxygenation level dependent effect-> haemodynamic response is slow so remains for 12-15 secs after activity stops
-> only an indirect measure, many areas involved in one task! effected by noise
-> reduced response in Tourette’s
Neural recording methods
Single cell recording
Electroencephalogram
Event related potentials
Magnetoencephalograpy
Electroencephalogram
Measures brain activity in living brain
Provides continuous recording of overall brain activity from scalp electrodes
Populations of post synaptic neurones measured
-> sleep, depth of anaesthesia, epilepsy and brain damage, normal brain
EEG profiles change depending on brain state
Event related potentials
Evoked electrical activity specifically related to sensory, motor or cognitive events
Average of each one second phase on EEG is ERP
Coarse resolution
Relies on modelling of source dipoles