Behaviour and Memory

Question 1

Name the 5 ways drugs can effect neurotransmission

Answer 1

synthesis, storage, release, binding, reuptake

Question 2

if synthesis decreases…

Answer 2

reduction of neurotransmitter = less to be transmitted each time action potential sent

Question 3

If storage decreases (leaky vesicle)…

Answer 3

less neurotransmitter across cleft = weaker message

Question 4

If receptors are blocked…

Answer 4

… blocked receptors = less graded potential in post cell

Question 5

If reuptake process inhibited…

Answer 5

… neurotransmitter molecules remain in cleft area for longer = stronger message.

Question 6

What is an agonist?

Answer 6

A drug that binds to the receptor of the cell and triggers a response

• Mimics a naturally occurring substance
• Response created even without signal

Question 7

What is an indirect agonist?

Answer 7

A drug that enhances release/action of an endogenous neurotransmitter
- Increases synthesis, binding

Question 8

What is an antagonist?

Answer 8

blocks or suppress agonist-mediates responses

Question 9

How does a DBS work?

Answer 9

Pulse generator stimulates neurons, causing them to fire = smooth movement for Parkinsons patients