Behavioral Medicine & Substance Abuse Flashcards
A 3-year-old girl is brought in by her mother after she had a temper tantrum, held her breath until she turned blue, and passed out. Her mother is worried that she had a seizure because she had some tonic-clonic movements as well.
What should be the next step in management of this child?
Reassurance
Breath-holding spells are benign—there are no long-term effects or brain injury. There are 2 forms of breath-holding temper tantrums:
- The cyanotic form, in which the face turns blue until breathing returns
- The pale form, in which the face turns pale due to vasovagal syncope
Cyanotic episodes are preceded by several shrill cries; pallid spells are preceded by an injury, often with no cries or only one subsequent cry.
Reports of anabolic steroid abuse in high school athletes were brought to the attention of the team physician. You are asked to counsel athletes about the adverse effects of anabolic steroids.
What adverse effects would you highlight for this target audience?
Acne, Hirsutism, Gynecomastia, Testicular Atrophy, Azoospermia, Depression, Mania, Rage
Anabolic androgenic steroids are used by athletes to increase both muscle mass and strength. However, they come with a wide range of adverse effects. In addition to those listed above, some of them are:
- Premature closure of growth plates resulting in shorter-than-expected height
- Cardiac, liver, and kidney toxicities
- Cardiac arrhythmias and cardiomyopathy
- Hepatic adenomas and carcinomas
- Cholemic nephrosis related to hyperbilirubinemia
If all this is not enough, suicidal ideation and suicides have been associated with withdrawal.
A 2-year-old male with no prior health problems presents with a history of “head banging.” Most commonly it occurs at bedtime and occasionally in the middle of the night.
What EEG pattern would you expect to see in this child?
Normal
Head banging occurs in 5–15% of “normal” children. It typically begins at ∼ 8–9 months of age, and the behavior usually stops by 4 years of age. Do not order an EEG or an imaging study to evaluate these children. Reassurance is best. This is different from children with intellectual disabilities or autism, for whom head banging is part of their condition. In these cases, helmets or medications may be required to prevent or lessen the banging.
An otherwise healthy 10-year-old boy presents for a behavior consult with:
- 3-year history of eye blinking/facial twitching
- 1-year history of vocal barks
- Recent progression to foul utterances
What is the most likely diagnosis?
Tourette Syndrome
Tourette syndrome is the most severe tic disorder. DSM-5 diagnostic criteria include multiple motor/vocal tics present for at least 1 year, no tic-free interval > 3 months, onset prior to 18 years of age, and lack of underlying medical cause. Most cases are successfully managed with cognitive behavioral therapy, though if comorbidities exist (e.g., ADHD, obsessive compulsive disorder [OCD], oppositional defiant disorder [ODD]), tics often improve with treating the underlying condition. Of note, stimulants used to treat ADHD often unmask tics but do not cause them.
Maladaptive behaviors (e.g., tantrums, aggression, mood swings, self-injurious behavior) are common in children with autism spectrum disorder (ASD).
What medication is usually prescribed to treat these behaviors?
Risperidone
Children with maladaptive behaviors typically respond well to risperidone. Risperidone is known to cause increased prolactin levels; therefore, get baseline prolactin levels before starting treatment.
A 13-year-old boy is diagnosed with ADHD. He is placed on stimulant medication.
When children with ADHD are placed on stimulant medication, what disorder may be unmasked?
Tic Disorder
Stimulant medication used to treat ADHD may unmask (but not cause) a tic disorder; discontinuation of the stimulant is only recommended if the tic becomes more of a problem than the ADHD. ADHD and tics are commonly comorbid conditions, and use of methylphenidate generally improves the ADHD without worsening the tic disorder.
What is the best way to manage a sleep problem in a toddler (e.g., waking up in the middle of the night)?
Have a Regular Bedtime Routine
The routine may be to read a book, take a bath, etc. The key is consistency and sticking with it. Verbal reassurance to the child (and to the parent!) eventually wins out. Encourage parents to put their children to bed while they are awake, drowsy but not yet asleep.
An adolescent presents to the emergency department after binging on methamphetamines. Body temperature and systemic blood pressure are elevated, and he has an irregular heart rate.
How would you manage this patient?
Cooling Blankets, Larozepam or Diazepam.
Methamphetamine (a.k.a. “ice”) can be administered by mouth, through inhalation (smoking), through mucous membranes, or by injection. Effects can be dose related. Tachycardia and dysrhythmias can be seen at lower doses, while higher doses are associated with hyperpyrexia, ventricular irritability, elevated blood pressure, and seizures.
Behavioral findings include agitation and delusional behaviors. These can be treated with haloperidol or droperidol.
Following her 8-year-old’s normal wellness exam, a recently divorced mother confidentially tells you that her daughter:
- Has had a recent decline in schoolwork
- Frequently complains of stomachaches
- Blames herself for her parents’ separation
What recommendation would you have regarding this child’s behavioral changes?
Referral to a Qualified Mental Health Professional
Divorce is common in the United States. Maladjustment disorders often develop from inconsistent parenting styles, change in financial situation, and parental conflict. Be alert for signs of distress in your pediatric patients, such as depression, withdrawal, somatic complaints, and self-blame. As adults, these individuals are at risk for self-esteem and relationship issues of their own. Early referral to psychiatrists or psychotherapists can be helpful.
An adolescent with known history of substance abuse is arrested on a drunk driving charge and placed in jail. He has been held in jail for about 6 hours and is now showing noticeable yawning.
What is one of the illicit drug categories that he likely uses?
Opiates (Heroin)
Heroin withdrawal occurs about 8 hours after the last exposure. One of the first signs is yawning. Then lacrimation, mydriasis, insomnia, “goose flesh,” diarrhea, and systolic hypertension occur. Diazepam is helpful for the withdrawal symptoms, but the patient should be managed in a professional setting.
A 1-month-old infant seems to have difficulty feeding and becomes diaphoretic with feeding. Also, he cries excessively.
What is the most likely diagnosis?
Congenital Heart Disease
In this case, suspect some form of congenital heart disease because diaphoresis is uncommon in infants. Look for an anomalous left coronary artery in a “colicky-sounding” infant. The crying could be from the baby having angina!
A 17-year-old boy presents with:
- Ataxia
- Euphoria
- Verbal abusive language uncharacteristic for him
- Thrashing out and difficult to control because he says people are trying to “get him”
What illicit drug did he likely get exposed to?
PCP (Phencyclidine)
PCP causes the GI effects cramping, diarrhea, and hematemesis and the neurologic effects euphoria, nystagmus, ataxia, and hallucination. Higher doses result in frank psychosis and verbal abusive language. Even higher doses can result in cardiac arrhythmia and seizures.
A 2-year-old girl started screaming after being told “no” to a second cookie. She suddenly:
- Gave a few shrill cries followed by brief apnea
- Lost consciousness
- Experienced facial cyanosis until breathing resumed
What caused this child’s apnea?
Breath-Holding Spell (Cyanotic Type)
Breath-holding spells (cyanotic type) are often associated with temper tantrums. Though frightening, they are benign. Temper tantrums are common in the 2- to 4-year-old age group, with 20% of 2-year-olds having daily tantrums. Encourage parents to avoid angry responses to tantrums so as not to reinforce the negative behavior. Offering children choices gives them a sense of control and often prevents a tantrum, though once a tantrum has begun, it’s best to ignore the behavior.
An adolescent presents for counseling because of drug dependence.
What are some of the most common risk factors associated with the development of substance abuse?
Household Drug Use (Especially by Parents!); Peer Group Drug Use; Untreated ADHD
The consequences of substance abuse can be devastating, frequently leading to accidents, injuries, and death. Associated high-risk sexual behaviors can result in unwanted pregnancy and STIs (including HIV). Continued abuse of substances can result in fetal anomalies (e.g., fetal alcohol syndrome). Substance abuse is linked to delinquency and crime. Long-term abuse has been associated with neuropsychiatric impairment.
A 20-month-old boy presents for his wellness exam with:
- No intelligible words
- Poor eye contact
- Persistent rocking/arm flapping behavior
The mother has concerns regarding his recent MMR vaccine.
What is the most likely diagnosis?
Autism Spectrum Disorder (ASD)
ASD is a biologically based, life-long, neurodevelopmental disorder characterized by impaired social communication and repetitive and restricted behaviors and interests. It is thought to be caused by genetically altered brain development resulting in the neurobehavioral phenotype. In the U.S., 1 in 68 children are affected, with a male predominance. ASD is more common in certain genetic conditions (e.g., TB, fragile X syndrome, untreated PKU). Overwhelming research evidence supports no causal relationship with vaccines.
What mental health disorder is characterized by excessive, unrealistic fears that interfere with daily activities?
Anxiety Disorder
Younger children often fear things like separation from a parent, animals, heights, and the sight of blood. Adolescents have the added fears of academic failure and the lack of peer approval. What separates normal situational anxiety or fear from anxiety disorder is that the latter involves the presence of restlessness, irritability, difficulty with concentration, sleep disturbance, muscle tension, and fatigue that interferes with daily life. Treat anxiety disorders with cognitive behavioral therapy (CBT). If there is no improvement, a selective serotonin reuptake inhibitor (SSRI) can be added. Comorbidity exists with ADHD, oppositional defiant disorder (ODD), and depression.
A healthy teen presents to the emergency department following a syncopal episode after huffing room deodorizer.
What will you look for in your evaluation of this patient?
Hypotension, Cutaneous Flushing Followed by Vasoconstriction, Tachycardia, Inverted T Waves and ST Depression
Huffing refers to the inhalation of fumes or vapors from a closed container such as a paper bag, balloon, or soda can. Inhalants are abused for their psychoactive properties. They tend to be short-acting, so dosing tends to be repeated in order to prolong the euphoria.
Methemoglobinemia has been reported with amyl nitrate. When this occurs, the SaO2 is decreased. Treatment is supportive.
What are the stages of grief that adolescents experience with the death of a close family member?
Denial, Anger, Bargaining, Depression, and Acceptance
The death of a close family member is one of the most stressful events that a child can experience. Young children can have eating, sleeping, speech, and bowel/bladder disturbances. School-age children may experience depression, behavioral issues, and an obsession with their own health. Adolescents, like adults, experience the 5 stages of grief.
A 16-year-old boy presents with a 3-week history of:
- Decreased appetite
- Hypersomnia
- Fatigue
- Decreased ability to concentrate
- Weight loss
- Irritability
- Diminished interest in playing soccer (his favorite sport)
What should you consider as a possible diagnosis?
Depression
When adolescents present with depressed mood or irritability, particularly with diminished interest or lack of pleasure in activities they used to enjoy, think depression. Consider a major depressive disorder (MDD) if, for 2 consecutive weeks, they have ≥ 5 of the following symptoms, with at least 1 of them being #1 or #2: 1) depressed mood/irritability; 2) diminished interest in activities; 3) weight changes and appetite changes; 4) sleep changes; 5) psychomotor agitation or disability; 6) fatigue and energy loss; 7) feelings of worthlessness or excessive guilt; 8) decreased ability to concentrate or think; or 9) recurrent thoughts of self-harm. Always be sure to get a thorough history and think of drug use as well.
A mother brings in her 8-year-old child with a history of 2 prior admissions for bacteremia—one with E. coli and the 2nd with a mixture of organisms, including E. coli and Serratia. The mother is a nurse in another hospital.
The child now presents with the following, fever, hypotension, and shock.
Previous workup for immune dysfunction was negative. The mother seems happy that the child is ill again and is excited to be coming into the hospital.
What diagnosis should be entertained at this point?
Factitious Disorder Imposed by Another (Formerly Munchausen Syndrome by Proxy)
Factitious disorder imposed by another is a bizarre disorder, considered to be a form of child abuse, in which the caregiver-child relationship is “disturbed.” The mother is almost always the one involved, and she is commonly in the health care profession. She is deliberately dishonest about the history of illness in her child and/or harms the child to “create” an illness. Be suspicious on the exam if a child presents with recurrent, serious illness that cannot be satisfactorily explained—recurrent E. coli bacteremia in an 8-year-old is very unusual, especially with a mixture of Gram negatives (think about mom injecting feces in the child or something similar).
You are asked to develop a substance abuse program for high school students.
What is the most frequently abused substance in this target age group?
Alcohol
Most teenagers have tried alcohol by the time they are seniors in high school. Most underage drinking is done in the form of binge drinking. Binge drinking refers to the consumption of > 4 drinks within a 2-hour period.
Impaired judgement, abnormal behaviors, and altered level of consciousness can be seen with elevated blood alcohol levels. The diagnosis of acute alcohol intoxication can be made with serum or breath alcohol levels.