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Antibiotika > Behandlingar > Flashcards

Behandlingar Flashcards

1
Q

PcV

A

strep, pneumokocker

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2
Q

PcG

A

G+ kocker (strep, PnC)
H influenzae
meningokocker

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3
Q

ampicilin, amoxicillin

A

G+: kocker, E fecalis, Listeria

G-: H influenzae, E coli, Pasturella

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4
Q

amoxicillin + klavulansyra (B-laktamashämmare)

A

som amoxicillin
hud-/mjukdelsinfektioner
biverkningar GI

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5
Q

isoxazolyl-Pc

A

stabilt mot staf-penicillinas

strep-infektioner

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6
Q

cefalosporiner indikationer

A

G-, blandinfektioner, empirisk beh innan etiologi fastställts

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7
Q

cefalosporiner effekt mot G+/G-?

A

när aktivitet mot G- ökar, minskar den mot G+

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8
Q

cefotaxim

A
  • brett G+/G-

- enterokocker resistenta

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9
Q

ceftazidim

A

bred G- (aerob) täckning (Pseudomonas!)

sämre G+

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10
Q

Cefadroxil

A

G+

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11
Q

ceftibuten

A

G-

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12
Q

piperacillin + tazobactam

A
  • betalaktam + B-laktamashämmare
  • mkt brett! G+, G-
  • anaerober, pseudomonas
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13
Q

pip-tazo indikationer

A
  • bukinfektion
  • neutropen feber
  • pseudomonas
  • svår sepsis
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14
Q

karbapenemer

A
  • G+
  • G- anaerober
  • pseudomonas
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15
Q

vilka bakt tas ej av karbapenemer?

A
  • e faecium
  • MRSA
  • MRSE
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16
Q

indikation karbapenemer

A
  • bukinfektioner
  • neutropen feber
  • svåra/nosokomiala inf
17
Q

aminoglykosider avdödningstyp

A

baktericid, proteinsynteshämmare. konc.beroende

18
Q

aminoglykosider

A
  • enterobacterriacae
  • s aureus
  • pseudomonas
  • synergism med B-laktam vid streptokock, enterokockendokardit
19
Q

glykopeptider

A
  • G+ (MRSA, MRSE, E fecalis, feacium, C diff)

- OBS! stor, passerar ej BBB

20
Q

hur administreras glykopeptider?

A

i.v., absorberas ej från GI

21
Q

biverkan glykopeptider

A

red man syndrome - pseudoallergisk reaktion

22
Q

avdödning glykopeptider

A

bakteristatisk

23
Q

folsyreantagonister (trimetoprim, sulfa)

A
  • breda! G+, G-
24
Q

indikation folsyreantagonister

A

prostatit, KOL-exacerbation, PCP, preop

25
Q

kinoloner avdödning

A

baktericida, koncentration, biofilm

26
Q

ciprofloxacin

A
  • kinolon
  • G-, pseudomonas
  • sämre G+
27
Q

meningokockprofylax

A

ciprofloxacin

28
Q

levofloxacin

A
  • bättre G+ täckning än cipro

- mykoplasma, chlamydophila, legionella, TBC

29
Q

moxifloxacin

A
  • bäst G+ av kinoloner (cipro/levo)
30
Q

tetracykliner

A
  • brett spektrum

G+, G-, aerober, anaerober, mycoplasma, chlamydophila, rickettsia

31
Q

tetracykliner biverkning

A

inlagring i ben/emalj (gravida, barn <8 år)

fototoxisk

32
Q

tetracykliner avdödning

A

bakteriostatisk

hämmar proteinsyntes

33
Q

makrolider

A
  • G+

- moraxella, bordetella, mycoplasma, chlamydophila, legionella

34
Q

makrolider clearance

A

levern

35
Q

makrolider biverk

A

GI, kärlretande, förlängd QT-tid

36
Q

linkosamid

A
  • G+

Antibiotika (4 decks)

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