BEERS Flashcards

1
Q

Anticholinergic Burden

A

cumulative effect of taking one or more anticholinergic drugs. Is a strong predictor or physical and cognitive impairment in elderly.

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2
Q

Anticholinergic Drugs

A

medications that block the action of acetylcholine (a neurotransmitter). (a large number of drugs)

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3
Q

Extrapyramidal symptom-causing agents

A

(aka Drug Induced Movement Disorders, EPS)
Common side effect of dopamine-receptor blockers. (antipsychotics, lithium, SSRI’s, TCA tricyclic antidep, stimulants). Esp. Lithium and risperidone.

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4
Q

Extrapyramidal Symptoms

A

dystonia, parkinsonism, lip smacking, neck twisting, tardive dyskinesia.

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5
Q

Anticholinergic Burden Scale (ABS)

A

Scale that distinguishes risk of drugs by 1,2,3 points. >= 3 is clinically relevant risk.

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6
Q

BEERS
Anticholinergic drug:
First-generation Antihistamines

A

“ine” suffix.
s/s: confusion, dry mouth, constipation
Rec: avoid

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7
Q

BEERS
Anticholinergic Drug
Antiparkinsonian Agents

A

Benztropine, trihexyphenidle

Rec: Avoid

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8
Q

BEERS
Anticholinergic drug
Antispasmotics

A

“ine” suffix

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9
Q

BEERS, CV

Digoxin

A

rec: NOT first line of defense against Afib or CHF. Especially bad for Kidneys.

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10
Q

BEERS, CV

Amiodarone

A
  • works to maintain sinus rhythm (afib) however high toxicity risk.
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11
Q

BEERS, CNS

Antidepressants

A
alone, or in combination
rec:  Strongly avoid
Amoxapine 
Clomipramine 
Desipramine 
Doxepin >6 mg/d 
Imipramine 
Nortriptyline 
Paroxetine 
Protriptyline 
Trimipramine
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12
Q

BEERS, CNS

Antipsychotics

A

rec: strongly avoid
Risk: CVA, cognitive decline, increased rate of dementia.

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13
Q

BEERS, CNS

Barbituates

A

“barbitol” suffix
sedative, sleep-inducing
Rec: strongly avoid
Risk: risk of OD at low doses

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14
Q

BEERS, CNS

Benzodiazepines

A

“epam” suffix
lowers brain activity, anxiety, insomnia, seizures.
Rec: strongly avoid
Risk: falls, fractures, delirium, cognitive impairment. Remains in system for a long time.

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15
Q

BEERS, endocrine

Estrogen

A

rec: Strongly avoid
Risk: increased risk of breast CA,

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16
Q

BEERS, endocrine

Growth Hormone

A

Rec: strongly avoid
Risk: edema, arthralgia, impaired fasting glucose

17
Q

BEERS, endocrine

Insulin, sliding scale

A

Rec: moderately avoid
Risk: high for hypo or hyper glycemia.

18
Q

BEERS, GI

Proton-Pump Inhibitor

A

Rec: strongly avoid
Risk: C-diff, bone loss, fracture

19
Q

BEERS, Pain medications

NSAIDS

A

Rec: avoid chronic use
Risk: peptic ulcers and GI bleed.

20
Q

BEERS, pain medications

Indomethacin, Ketorolac

A

Rec: moderately avoid
Risk: Indomethacin - CNS side effects
Ketorolac - Inc. GI bleed, Kidneys

21
Q

BEERS, pain medications

Skeletal mm relaxants

A

Rec: moderately avoid
Risk: anticholinergic effects, sedation, fractures

22
Q

BEERS, Genitourinary

Desmopressin

A

Rec: moderately strong

High Risk: Hyponatremia