BDS2+BDS3 EBD Flashcards
Define confidence interval
Range of values that a true population effect is likely to lie between
CI overlaps 1 =
Insufficient evidence
Gold standard study
RCT
Strongest evidence of effectiveness of tx
Design elements of RCT
Inclusion/exclusion criteria
Control
Randomisation
Blinding
Disadvantages of RCT
Difficult to design + conduct
Risk of bias
Function of a case report
Report on single person - hypothesis generation
Disadvantage of case report
Lack of control group
Function of cross sectional study
Estimate prevalence of disease + potential risk factors
Disadvantages of cross sectional study
Confounding
Recall bias
Causality
Function of case control
Look for causes of disease
Disadvantages of case control
Confounding
Recall bias
Function of cohort
Estimates incidence + cause of disease
Disadvantages of cohort
Confounding
Expensive
Blinding difficult
ARD overlaps 0 =
Not statistically significant (no risk/benefit)
Advantages of a split mouth design
Each participant acts as own control (decreases inter individual variation)
Disadvantages of a split mouth design
Carry across effects
Selection of pts might limit external validity
Define incidence
Number of new cases in a particular time period
Define prevalence
Frequency of disease in a population at a particular time period
What is the chain of infection
Infectious agent
Reservoir
Portal of exit
Mode of transmission
Portal of entry
Susceptible host
Sinner cycle
Time
Temp
Chemicals
Energy