BB Flashcards
ABO Discrepancy
situation where the forward typing does not agree with the backward typing
Absorption
removal of specific antibody from a mixture of antibodies using cells of known specificity
Active Immunization
production of antibody after antigenic exposure
Additives
chemical substance added to prolong shelf life to 42 days
Agammaglobulinemia
rare condition; absence of antibody
Agglutination
clumping of particulate antigen to specific antibodies
Hemagglutination
clumping of antigen from RBC to specific antibody
Allele
alternative form of gene occupying a given locus
Amniocentesis
process pf collecting amniotic fluid
Amniotic Fluid
albuminous fluid in the amniotic sac which provides nutrients to the fetus
Amorph
silent gene: does not produce a detectable antigen (ex: O gene)
Anamnestic Response
secondary immune response; production of antibody after secondary exposure
Anaphylaxis
severe hypersensitivity reaction of antibodies against IgA (IgA deficient patients exposed to IgA antibody)
Antenatal
before birth
Antibody
immunoglobulin; protein substance secreted by plasma cells in response to antigenic stimulation
Alloantibody
against foreign antigen of same species
Autoantibody
against self antigens
Atypical Antibody
unexpected antibody; antibodies other than naturally occurring anti-A and anti-B
Naturally Occurring Antibodies
isoantibodies: anti-A and anti-B
Monoclonal Antibody
derived from single clone antigen
Polyclonal Antibody
from more than one antibody producing plasma cells
Antibody Potentiators
reagents used enhance antigen antibody reaction
Antibody Screening Test
to detect immune antibody using phenotype O cells
Antigen
foreign substances that stimulate antibody production
Antigenic
ability to illicit immune response
Antigram
table to phenotype group O cell showing different antigens and identify immune antibody
Antihuman Globulin Reagent
Coombs’ serum; secondary antibody against IgG and complement
Monospecific Antihuman Globulin Reagent
either IgG pr complement C3
Polyspecific Antihuman Globulin Reagent
both IgG and complement C3
Antihuman Globulin Test
Coombs’ test; antibodies directed against human globulin to aid in detection of RBC synthesized by IgG alloantibodies/autoanyibodies and complement
Direct Antiglobulin Test
in vivo cell sensitization
Indirect Antiglobulin Test
in vitro cell sensitization
Antiserum
commercially prepared reagent of known antibody specificity
Antithetical
antigens controlled by pair of allelic genes
Apherises
blood collection wherein whole blood is withdrawn and processed
Plateletpheresis
removal of platelet
Leukapheresis
removal of leukocytes
Plasmapheresis
removal of plasma
Autoabsorption
antibody removal using patient’s own antigen
Autocontrol
PS-PR ( Patient Serum - Patient Red Cell); to detect antibody
Avidity
strength of antigen antibody reaction