Basics of Aseptic Technique Glossery

Question 1

ACD Automated Compounded Devices:

Answer 1

Devices used to prepare TPN solution. The base ACD prepares the vase components of the TPN. A second additives ACD add most or all of the additives or other components of the TPN.

Question 2

Air Bioburden:

Answer 2

The level of microorganisms present in the air.

Question 3

Anteroom:

Answer 3

Room ajoined to the clean room used for nonaseptic activities such as gowning and handling of stock

Question 4

Aseptic Preperation or Aseptic Processing:

Answer 4

The technique involving procedures designed to preclude contamination (of drugs, packaging, equitment, or supplies) by microorgamisms during processing.

Question 5

Batch Preperation:

Answer 5

Compounding of multiple sterile preperation units, in a single discrete process, by the same individuals and carried out during one limited time period.

Question 6

Biohazard:

Answer 6

An infectious agent presenting a real or potential risk to humans and the enviromnet.

Question 7

Biological Safety Cabinet (BSC):

Answer 7

An engeneering / ventilatin control device designed as a primary barrier for handling hazardous biological materials. Infectious agents must be used with a BSC, not in a laminar airflow workbench or hood.

Question 8

Carcinogen:

Answer 8

Any Cancer-producing substance

Question 9

Carrying Costs, or Holding Costs:

Answer 9

All costs associated with inventory investment and storage.

Question 10

Chemotherapy:

Answer 10

The treatment of desease by chemical means; first applied to the use of chemicals that affect the causative organism unfavorably but do not harm the patient; currently used to describe drug (chemical) therpy of neoplastic diseases (cancer).

Question 11

Chemotherapy Drug:

Answer 11

A chemical agent used to treat diseases. The term usually refers to a drug used to treat cancer.

Question 12

Chemotherapy Glove:

Answer 12

A medical glove that has been tested by the American Society for Testing and Materials (ASTM) D 6978-05 Standard for Assessment of Resistance fo Medical Gloves to Permeation by Chemotherapy Drugs.

Question 13

Clean Room:

Answer 13

A room in which the concentration of airborne particles is controlled; that is constructed and used in a manner to minimize the introduction, generation, and retention of particles inside the room; and in which other relevant variables (i.e., temperature, humidity, and pressure.) are controlled as necessary.

Question 14

Clean Zone:

Answer 14

Dedicated space in which the concentration of airborne particles is controlled; that is constructed and used in a manner that minimizes the introduction, generation, and retention of particles inside the zone, and in which the other relevant variables (i.e., temperature, humidity, and pressure) are controlled as necessary. The zone may be open or enclosed and may or may not be located within a clean room.

Question 15

Closed System:

Answer 15

A device that does not exchange unfiltered air or contaminants with the adjacent environment.

Question 16

Closed System Drug-Transfer Device:

Answer 16

A drug-transfer of ingredients to prepare a medication for patient use. This activity would include dilution, admixture, repackaging, reconstitution, and other manipulations of sterile preparations.

Question 17

Compounding:

Answer 17

The mixing of ingredients to prepare a medication for patient use. This activity would include dilution, admixture, repackaging, reconstitution, and other manipulations of sterile preparations.

Question 18

Contamination:

Answer 18

The deposition of potentially dangerous material where it is not desired, particularly where its prescience may be harmful or constitute a hazard.

Question 19

Contingency Program:

Answer 19

A program or procedure put in place by facility as backup for unseen circumstances such as high risk levels of bioburden.

Question 20

Controleld Area:

Answer 20

The area designated for preparing sterile preparations. This is referred to as the buffer zone (i.e., the clean room in which the laminar airflow work-bench is located) by USP.

Question 21

Coring:

Answer 21

Introducing particulate matter (in the form of a plastic or rubber core or plug) into a sterile fluid through the process of penetrating the outer seal of a vial with a needle.

Question 22

Engineering Controls:

Answer 22

Devices designed to eliminate or reduce worker exposures to chemical, biological, radiological, ergonomic, or physical hazards. Examples include laboratory fume hoods, glove bags, retracting syringe needles, sound-dampening materials to reduce noise levels, safety interlocks, and radiation shield.

Question 23

Enteral:

Answer 23

Delivery of medication by mouth.

Question 24

Epidural Route of Administration:

Answer 24

Medication injected on or outside the outermost layer of the covering of the brain or spinal cord.

Question 25

Exposure:

Answer 25

The condition of being subjected to something, as to chemicals, that may have a harmful effect.

Question 26

Acute Exposure:

Answer 26

Exposure of short duration, usually exposure of heavy intensity; chronic exposure is of long duration, continues or intermittent and usually referring to exposure of low intensity.

Question 27

Formulary:

Answer 27

An organized list of drugs approved for use in an organization or by a prescription drug benefit plan. Also a list of drugs approved by third party for reimbursement.

Question 28

Hazardous Drug:

Answer 28

Any drug identified by at least one of the following six criteria; carcinogenicity, teratogenicity or developmental toxicity, reproductive toxicity in humans, organ toxicity at low doses in humans or animals, genotoxicity, or new drugs that mimic existing hazardous drugs in structure or toxicity.

Question 29

High-Efficiency Particulate Air (HEPPA) Filter:

Answer 29

High-efficiency particulate air filter rated at 99.97% efficient in capturing 0.3- micron-diameter particles.

Question 30

Intraarticular Rout of Administration:

Answer 30

Medication is injected into a joint, such as a knee or elbow.

Question 31

Intramuscular Route of Administration:

Answer 31

Direct injection of medication into a large muscle mass where the drug is then adsorbed from the muscle tissue into the blood stream.

Question 32

Intraocular:

Answer 32

Delivery of medication into the eye.

Question 33

Intraperitoneal:

Answer 33

Medications given into the peritoneal or abdominal cavity.

Question 34

Intravenous Route of Administration:

Answer 34

Medications are introduced into the body through a needle placed directly in a vein.

Question 35

Isolator:

Answer 35

A closed system made up of four solid walls, an air-handler system, and transfer and interaction devices. The walls are constructed so as to provide surfaces that are cleanable with covering between wall junctures. The air-handeling system provides HEPA filtration of both inlet and exhaust air. Transfer of materials is accomplished through air locks, glove rings, or ports. Transfers are designed to minimize the entry of contamination. Manipulations can take place through either glove ports or half-suits.

Question 36

Just-in-time product inventory:

Answer 36

An inventory management system that ensures that products are ordered and delivered when they are needed for patient care.

Question 37

Laminar Airflow Workbench / Hood (LAFW) (LAFH)

Answer 37

A primary engineering control used for aseptic compounding categorized by the use of two filters to reduce contaminants within the hood.

Question 38

Osmolarity:

Answer 38

A property of solution that depends on the concentration of the solute per unit of total volume of solution.