Basic structure and function of skeletal muscles Flashcards

1
Q

Give some examples of function of muscles

A
Provides us with our ability to move
Regulate organ volumes
Allow us to communicate with one another
Consumes ATP in order to produce body heat
Maintains posture
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2
Q

Name the 3 types of muscles

A

Smooth, skeletal and cardiac

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3
Q

Where would you find smooth muscle

A

On the walls of internal organs

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4
Q

Where would you find cardiac muscle

A

In the heart

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5
Q

Where would you find skeletal muscle

A

Attached to the skeleton via tendons or indirectly via a connective tissue called aponeurosis

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6
Q

Order of the grouping of skeletal muscle

A

Bundles of muscle fascicles
Bundles of muscle fibres
Bundles of myofibrils
Bundles of myofilaments

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7
Q

What are myofibrils composed of

A

Protein filaments

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8
Q

What are myofilaments responsible for

A

Muscle contraction

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9
Q

What are the 3 layers of connective tissue that muscles are organised into?

A

Endomysium, perimysium and epimysium

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10
Q

What does endomysium surround

A

Each muscle fibre

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11
Q

What doe perimysium surround

A

Groups muscle fibres into muscle fascicles

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12
Q

What is the function of perimysium?

A

To prevent any damage to the muscle fascicles

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13
Q

Why is there a nutrient storage in perimysium?

A

It has vascularity - it contains capillaries and nerve fibres

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14
Q

What does epimysium surround

A

An entire skeletal muscle

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15
Q

What does epimysium seperate

A

The muscle from surrounding connective tissue and muscles

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16
Q

What is a muscles sarcolemma

A

The plasma membrane of a muscle fibre

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17
Q

Describe the sarcolemma’s role in action poteionals

A

Recieves electrical stimuli and conducts an action potential to the muscles internal structures

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18
Q

Describe transverse tubules

A

Forms where the sarcolemma is invaginated,

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19
Q

How do transverse trabeculae recieve stimuli from the sarcolemma?

A

They penetrate through the muscle fibre

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20
Q

What does the sarcoplasmic reticulum contain?

A

A calcium storage

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21
Q

How are terminal cisternae formed?

A

When the s. reticulum becomes enlarged and forms bonds that wrap around the muscle fibre on either side of the t tubule

22
Q

What is the function of the terminal cisternae

A

To release calcium from the s. reticulum

23
Q

What do terminal cisternae trigger?

A

The contraction of myofibrils

24
Q

Are mucles single or multi nucleated?

A

Multinucleated

25
What does the sarcoplasm contain?
glycogen and myofibrils
26
What are myofibrils made of?
Composed of myofilaments that are organised into sarcomeres
27
Define a sarcomere
The basic functional unit of a myofibril
28
What is found at the I band
Actin
29
What is found at the z line
titin - marks the end of sarcomere
30
What is found at m line
myosin
31
What do you not find at the h zone
actin
32
What does myosin allow
Coupling hydroylis of ATP to conformational changes to the head region of the filament that enables it to bind and move along the actin filaments
33
What structual protein is found at the m-line of a sarcomere
myomesin
34
What structual protein is found at actin filaments
nebulin
35
What tructual protein links actin to the sarcolemma
dyotrophin
36
Name the 2 regulatory proteins of muscle contraction
Tropomyoin and troponin
37
What does tropomyosin regulate
uncovers myosin head during excitation and contraction
38
What is the role of troponin
binds to calcium forming a crossbridge link
39
Are skeletal muscles straited or non striated
striated
40
Are cardiac muscles straited or non striated
striated
41
Are smooth muscles straited or non striated
non striated
42
Are skeletal muscles voluntary or involuntary
voluntary
43
Are smooth muscles voluntary or involuntary
involuntary
44
Are cardiac muscles voluntary or involuntary
involuntary
45
In muscles where is acetyl cholinerase found
Acetyl cholinesterase is found in the synapse between nerve cells and muscle cells
46
Define muscle spindles
Muscle spindles are sensory receptors within the belly of a muscle
47
What is the function of muscle spindles
Muscle spindles primarily detect changes in the length of muscle.
48
What part of the sarcomere does not shorten during mucle contraction?
A band
49
How do leukocytes move to the site of injury
by diapedis
50
What is the function of titin
Maintains the alignment of thick filaments in the middle of the sarcomere