Basic Skin Immunology

Question 1

What T cells are mainly found in the epidermis

Answer 1

CD8+ t cells

Question 2

What Th cell is associated with psoriasis

Answer 2

Th1

Question 3

What Th cell is associated with atopic dermatitis

Answer 3

Th2

Question 4

What Th cell is associated with psoriasis and atopic dermatitis

Answer 4

Th17

Question 5

Where are T cells produced and sensitized

Answer 5

Produced in bone marrow and sensitized in the thymus

Question 6

Information on class 1 MHC

Answer 6

Found on almost all cells, presents antigen to cytotoxic T cells and presents endogenous antigens

Question 7

Information on class 2 MHC

Answer 7

Found on antigen presenting cells (B cells and macrophages), present to Th cells and present exogenous antigens

Question 8

Triggers for psoriasis

Answer 8

Bacterial pharyngitis, HIV and stress

Question 9

Drugs that trigger psoriasis

Answer 9

Beta blockers and lithium

Question 10

What hypersensitivities lead to an arthus reaction

Answer 10

Type 3 hypersensitivity