Basic Pharmacology (ch1) Flashcards

1
Q

ABSORPTION

A

process by which a drug is taken into the body and moves from the site of administration into the blood.

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2
Q

ADVERSE EFFECT

A

undesired, potentially harmful side of effect of drugs

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3
Q

AGONIST

A

drug molecule that binds to a receptor and causes a response

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4
Q

ANTAGONIST

A

drug that binds to specific receptor sites and prevents other medications from binding to these same sites, reversing or not allowing them to have an effect.

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5
Q

BIOAVAILABILITY

A

the extent to which an administered amount of a drug reaches the site of action and is available to produce its effects

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6
Q

BIOTECHNOLOGY

A

concepts of genetic engineering and recombinant dna technology

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7
Q

BIOTRANSFORMATION

A

process of changing the chemical composition of a drug from lipid-soluble molecules into water-soluble molecules that can be more easily excreted; usually takes place in the liver AKA drug metabolism.

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8
Q

BOLUS

A

entire dose of medication given at once

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9
Q

CONTRAINDICATION

A

condition when the use of given medication should be avoided.

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10
Q

DISTRIBUTION

A

process in which the circulatory system transports a drug throughout the body and drug molecules eventually diffuse our to the bloodstream to the sire of actions.

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11
Q

DURATION

A

time b/w onset and disappearance of drug effects.

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12
Q

EMULSION

A

medication contained in a mixture of water and oil bound together with an emulsifier.

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13
Q

ENTERAL

A

pertaining to the intestinal tract

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14
Q

EXCRETION

A

process of elimination of drug molecules from the body ; usually the urinary system.

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15
Q

HYPERSENSITIVITY

A

allergic response resulting from previous exposure to the drug or a similar drug; a type of adverse effect to a drug

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16
Q

IDOSYNCRATIC EFFECT

A

rare and unpredictable adverse effects of some drugs on individuals, in which the mechanism of the effect may not be known clearly or understood.

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17
Q

INDICATION

A

reason a medication is used to to treat a condition

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18
Q

LOCAL EFFECT

A

medication acts at the site of application

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19
Q

ONSET

A

time b/w administration of drug and the first appearance of effects

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20
Q

PARENTERAL

A

pertaining to any drug administration route other than the intestinal tract.

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21
Q

PHARMACODYNAMICS

A

study of how drug actions affect the body

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22
Q

PHARMACOKENETICS

A

study of how the body processes drugs

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23
Q

PLASMA PROTEIN BINDING

A

process in which some drugs molecules attach to albumins and globulins contained in blood plasma

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24
Q

RECONSTITUTED

A

mixing a powder with a liquid to form a solution

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25
SIDE EFFECTS
predictable but unintended effect of a drug
26
SOLUBILITY
characterisitic indicating how easily a drug can be dissolved in a fluid.
27
SOLUTION
mixture of drug particles fully dissolved in a liquid
28
SUSPENSION
mixture of undissolved drug particles floating in a liquid
29
SYNERGIST
drug that enhances the effect of another drug
30
SYSTEMIC EFFECT
medications act throughout the body
31
TOPICAL
32
What drug is given as an antidote to warfarin?
vitamin
33
The abbreviation PO represents which one of the following?
orally
34
Prescriptions must include all of the following information
name of the drug. route of administration of the drug. drug dosage.
35
A surgical patient is given a drug during surgery and suspects he or she is having a delayed allergic reaction to the drug, several days later. Which symptom indicates that the patient may be having a delayed drug reaction?
joint swelling
36
An order for a drug to be given as needed is called a _______________ order.
PRN
37
The abbreviation bid represents which one of the following?
twice a day
38
The time between the administration of a drug and the first appearance of its effects is called
onset
39
When a drug travels from the site of administration into the bloodstream, it is called
absorption
40
What does the abbreviation sos mean on a prescription?
once, if necessary
41
A drug that binds to a receptor and stimulates its function is said to be a(n) _______________ drug.
agonist
42
An anticoagulant drug is classified by its
therapuetic action
43
Which one of the following abbreviations indicates that a drug is to be given orally?
PO
44
Most drugs are excreted and eliminated by the
kidney
45
Which form of drug preparation tends to act more quickly?
gas
46
The study of drugs derived from natural sources is called
pharmacognosy.
47
Drugs are chemically altered via a process called metabolism in the
liver
48
How is antibiotic irrigation applied during surgery?
topical
49
All are terms used to describe the body’s response or reaction to medications, except hypersensitivity. idiosyncratic. contraindication. side effect.
contraindication
50
Volatile anesthetic agents are eliminated from the body via
the lungs
51
How is a medication administered by any route except the mouth?
parenterally
52
The abbreviation NPO represents which one of the following?
nothing by mouth
53
Which group of drugs is known as receptor blockers?
antagonists
54
Many antibiotics used in surgery come in _________ form and must be reconstituted.
powder
55
Which drug administration route causes many drugs to undergo the “first-pass effect”?
oral
56
Which drug form is used the least in the surgical department?
solid
57
Which one of the following terms is the study of the four basic processes of absorption, distribution, metabolism, and excretion in response to drugs?
Pharmacokinetics
58
How is an order for a drug to be given three times a day indicated on a prescription?
tid
59
Which one of the following types of drug binds to receptor site proteins and then inhibits a response
antagonist
60
Malignant hyperthermia is a(n) _______________ effect to certain drugs.
idiosyncratic (IDR)
61
Distribution of drugs within the body is carried out through which one of the following body systems?
circulatory
62
Demerol is an example of a
synthetic drugs
63
Which one of the following is not used for the classification of drugs?
source of origin
64
A drug that enhances the effect of another drug is called a(n)
synergist
65
Why would a local anesthetic, injected into an infected wound, not produce the intended effect?
Because the local anesthetic could not reach the site of action
66
Which one of the following abbreviations indicates an ointment form of a given drug?
ung
67
An expected but unintended effect of a drug is termed a(n) _______________ effect.
side
68