Basic Pharmacology (ch1) Flashcards
ABSORPTION
process by which a drug is taken into the body and moves from the site of administration into the blood.
ADVERSE EFFECT
undesired, potentially harmful side of effect of drugs
AGONIST
drug molecule that binds to a receptor and causes a response
ANTAGONIST
drug that binds to specific receptor sites and prevents other medications from binding to these same sites, reversing or not allowing them to have an effect.
BIOAVAILABILITY
the extent to which an administered amount of a drug reaches the site of action and is available to produce its effects
BIOTECHNOLOGY
concepts of genetic engineering and recombinant dna technology
BIOTRANSFORMATION
process of changing the chemical composition of a drug from lipid-soluble molecules into water-soluble molecules that can be more easily excreted; usually takes place in the liver AKA drug metabolism.
BOLUS
entire dose of medication given at once
CONTRAINDICATION
condition when the use of given medication should be avoided.
DISTRIBUTION
process in which the circulatory system transports a drug throughout the body and drug molecules eventually diffuse our to the bloodstream to the sire of actions.
DURATION
time b/w onset and disappearance of drug effects.
EMULSION
medication contained in a mixture of water and oil bound together with an emulsifier.
ENTERAL
pertaining to the intestinal tract
EXCRETION
process of elimination of drug molecules from the body ; usually the urinary system.
HYPERSENSITIVITY
allergic response resulting from previous exposure to the drug or a similar drug; a type of adverse effect to a drug
IDOSYNCRATIC EFFECT
rare and unpredictable adverse effects of some drugs on individuals, in which the mechanism of the effect may not be known clearly or understood.
INDICATION
reason a medication is used to to treat a condition
LOCAL EFFECT
medication acts at the site of application
ONSET
time b/w administration of drug and the first appearance of effects
PARENTERAL
pertaining to any drug administration route other than the intestinal tract.
PHARMACODYNAMICS
study of how drug actions affect the body
PHARMACOKENETICS
study of how the body processes drugs
PLASMA PROTEIN BINDING
process in which some drugs molecules attach to albumins and globulins contained in blood plasma
RECONSTITUTED
mixing a powder with a liquid to form a solution
SIDE EFFECTS
predictable but unintended effect of a drug
SOLUBILITY
characterisitic indicating how easily a drug can be dissolved in a fluid.
SOLUTION
mixture of drug particles fully dissolved in a liquid