Basic Pharmaceutica/terms/informatiln

Question 1

Absorption

Answer 1

Involves transport of drug across biologic membranes (skin, mucous membranes, stomach/intestinal lining, sub q or muscle tissue etc) to reach target tissue

Question 2

Adverse Effects

Answer 2

More severe side effects that may justify the discontinuation of a drug

Question 3

Affinity

Answer 3

(attraction) ability of drug to bind tonreceptor; lock and key theory

Question 4

Agonist

Answer 4

Compound that binds to specific receptor and stimulates biologic response; had affinity and efficacy

Question 5

Antagonist

Answer 5

Prevents stimulation of receptors; has affinity for specific receptors, but lacks efficacy (Narcan, given for OD due to increased affinity for narcotic receptors)

Question 6

Bioavailability

Answer 6

Portion of drug available to produce systematic effects

Question 7

Biotransformation

Answer 7

Breakdown/metabolism of drug

Question 8

Controlled Substance Act of 1970

Answer 8

Repealed almost 50 other laws written since 1914 that relate to the control of drugs. The new law is designed to improve the administration and regulation of controlled substances
(Schedule i, ii, iii, iv, v)

Question 9

Schedule I

Answer 9

High potential for abuse, with no current accepted medical use

Question 10

Schedule II

Answer 10

High potential for abuse, with current accepted medical use

Question 11

Schedule III

Answer 11

High potential for abuse but less than Schedule I and II