Basic Mechanical Ventilation Flashcards
what determines the pressure required to make gas flow down a tube
the flow rate x the resistance in the tubing
what determines the pressure required to inflate a balloon?
the volume to which the balloon is inflated divided by the compliance of the balloon
what determines the pressure required to make air flow down a tube AND inflate a balloon (this is the pressure required to inflate the lung)
this is AKA the inflation pressure
inflation pressure = (flow x resistance) + volume/compliance
what is the airway pressure
Paw is the inflation pressure + the pressure in the balloon at the end of expiration (PEEP)
Paw = (flow x resistance) + (volume/compliance) + PEEP
what is alveolar pressure
(volume/compliance) + PEEP
what is flow
volume/time
ways to improve oxygen in
- increase FiO2
- reduce shunting
ways to reduce shunting
increase PEEP or increase inspiratory time
ways to blow off CO2
increase resp rate or tidal volume
How does PEEP reduce shunting
Opens alveoli and keeps them open
why can inspiratory time be set as a function of flow
because flow is volume/time
name 3 respiratory complications of mechanical ventilation
nosocomial pneumonia
ventilator associated lung injury
gas trapping
three causes of ventilator associated lung injury
high pressures (barotrauma)
high volumes (volutrauma)
shear injury
difference between volutrauma and barotrauma
barotrauma is gas leak injury such as pneumothorax, pneumomediastium, pneumoperitoneum etc
volutrauma is a histological appearance similar to ARDS - complication of lungs being repeatedly extended to excessive volumes, its an acute lung injury
what is shear injury
from repetitive opening and closing of alveoli
when does gas trapping occur
when there’s insufficient time for alveoli to empty before the next breath
4 predisposing factors in gas trapping
- asthma or copd
- long inspiratory time (short expiratory time
- high respiratory rate (short expiratory time)
- large tidal volumes
how can you measure the degree of gas trapping
- gas trapping increases PEEP
- because this increase is not because of the extrinsic PEEP (that you set on the vent) it is part of intrinsic PEEP
what is intrinsic PEEP
its either described as PEEPtotal if this value is greater than PEEPe
or
PEEPi = PEEPtotal - PEEPe
How can you measure PEEPtotal
expiratory pause hold control on the vent
complications of gas trapping
- barotrauma
- cardiovascular compromise –> PEA cardiac arrest in extreme cases
effect on preload of ventilation
reduces preload:
- normally venous return is enhanced by negative intrathoracic pressures during inspiration
- during positive pressure ventilation venous return is impeded and preload is reduced
features of ventilation that would decrease preload
high inspiratory pressure
prolonged inspiratory time
higher PEEP
effects of ventilation on afterload
- afterload is dependent on transmural pressure of the left ventricle in that as Ptm goes up so does afterload
- Ptm = the intracavity pressure (Pic) - the pleural pressure (Ppl)
- therefore ventilating someone with increasingly high pressures will lead to a reduction in afterload
overall effect of ventilation on cardiac output
- ventilation decreases afterload and decreases preload
- both of these have differing effects on cardiac output
- overall effect of positive pressure ventilation on cardiac output depends on the contractility of the ventrical
- normal contractility –> decreased cardiac output
- decreased contractility –> increased cardiac output
what is volume pre-set assist control ventilation
- AKA VC-A/C on dragers
- operator sets tidal volume, I:E and minimum ventilatory rate
- both patient and ventilator can initiate breaths
- if the pt does not initiate breaths frequently enought then the ventilator will initiate for her
- characteristics of the breath are the same whether pt initiates or the vent initiates
advantages of volume pre-set assist control ventilation
-simple to set up
- guaranteed minimum minute ventilation
- rests muscles of respiration if set properly
Disadvantages of volume pre-set assist control ventilation
- not always synchronised with patient’s breathing
- pt may lead the ventilator
- inappropriate triggoring (e.g. hiccups) may lead to excessive minute ventilation
- can’t directly control pressures
- often requires sedation due to discomfort due to dyssynchrony
what is pressure pre-set assist control ventilation
- aka pressure control
- inspiratory pressure is set instead of tidal volume
- because of a constant pressure there is a high initial flow that falls to zero by the end of inspiration
- reducing inspiratory time may decrease tidal volume if there is still inspiratory flow at the end of inspiration
- extending inspiratory time beyond the point when inspiratory flow falls to zero does not increase the tidal volume
- can’t control the pressure and therefore a fall in compliance could lead to barotrauma
- equally an increase in airway resistance could lead to a higher airway pressure
advantages of pressure pre-set assist control ventilation
- simple to set
- avoids high inspiratory pressures
- rests muscles of respiration
- decelerating flow pattern gives better oxygenation
disadvantages of pressure pre-set assist control ventilation
- not always synchronised with the patient’s breathing
- inappropriate triggering (e.g. hiccips) may lead to excessive minute ventilation
- can’t control the tidal volume and a rise in resistance or fall in compliance could lead to inadequate ventilation
- often requires sedation to achieve patient ventilatory synchrony