Basic intro Flashcards
Public Health Framework
- Define the problem
- Identify risk and protective factors
- Develop and test prevention strategies
- Assure widespread adoption
Epidemiology:
The study of measuring dis-ease in different populations
Risk of dis-ease equation:
Number of cases of dis-ease
_________________________
Number of people in the population
Health:
The absence of death, disease or disability
Acronym for GATE Frame:
PECOT
PECOT:
Participants Exposure group (EG) One half of pop Comparison group (CG) Other section of pop Outcomes Time
Cohort study:
Also called follow up study, when a group is followed over time and relevant dis-ease events are counted. Description of study usually says “observed”. Results in a death rate e.g. deaths out of 1000 people per year
EGO and CGO:
Exposure group outcome
Comparison group outcome
EGO=
A/Exposure group (deaths in EG/population of EG)
CGO=
B/Comparison group (deaths in CG/population of CG)
Arrow to the right =
Incidence
EGO and CGO are called an incidence measure of occurrence when:
Dis-ease events are counted as they occur over a period of time. e.g. km per hour - must include time in the equation
EGO and CGO are called a prevalence measure of occurrence when:
People with dis-ease are counted at one point in time. eg: if a car had travelled 200,000km when we checked today
If you want to know how fast a car can go you measure:
Incidence (km per hour)
If you want to measure how worn out a car is you measure:
Prevalence (mileage)
Arrow straight down =
Prevalence
Which measure of occurrence gives more data and why?
Incidence because it is only determined by the dis-ease risk in a population and because it measures events, population and time
If it difficult to measure when a dis-ease event occurs or it occurs frequently, it is measured IF (yes/no) it has occurred over a period of time, this is a measure of:
Period Prevalence
Obesity, asthma attacks and diabetes are measured using _____
Period Prevalence
Cross sectional study:
Measuring everything at the same time
EG measuring alcohol consumption and drug consumption at the same time and studying the relationship between the 2
Relative Risk=
EGO/CGO
Relative risk doesn’t have:
Units
In what studies is a cohort study often inaccurate:
Diet/disease/drug alcohol use
How is death always measured and why:
Death is always a measure of incidence as it happens over time
Ecological study:
Comparing averages of whole countries rather than individuals
(e.g. NZ vs AUS rather than NZ men vs NZ women aged 30-50)
RCT stands for:
Randomised controlled trial
What is a randomised controlled trial?
Similar to a cohort study except participants are randomly allocated to EG and CG
Can you measure prevalence within a cohort study?
Yes, you can stop EG after a year of following EG and CG and taking a measurement
What are the benefits of RCT?
You have an equal chance of being in EG and CG so the outcome can only be due to the outcome of the exposure
Double blind:
Neither the participants nor the investigators know which intervention was given to which participant
Singe blind:
Only the participants are unaware of which intervention was given
In what situation is RCT the best type of study?
When answering questions about the effect of a treatment if it is both ethical and practical
Risk Difference:
Risk of one group - the risk of the other group (EGO-CGO or CGO-EGO)
If the risk of 1 group is 30/100 and the risk of the treatment group is 20/100 what is the effect of treatment?
10 per 100, reduction in the amount of disease, or the benefit of giving 100 people the treatment is 10 more people not dying
If EGO=CGO what is the risk difference?
0 - those given the treatment had the same outcome of those without the treatment, there is no difference in the risk of death whether treated or not treated
Risk ratio: (relative risk)
EGO/CGO or CGO/EGO
If the relative risk is 2/3, what is the risk reduced by?
1/3
For example if RR of disease without treatment is 0.66, the risk of t disease is 33% lower in that have been treated
If EGO=CGO what is the risk ratio (or relative risk)?
1
If you are told you can reduce the risk by 50% what do you need to ask yourself?
Are they subtracting one risk from the other or dividing them
How do you all the difference between relative risk and risk difference?
Risk difference has units (deaths/population/time) while relative risk has no units (due to cancelling out)