Basic Info Flashcards
describe the location of the adrenal glands
sit adjacent to the kidney
adrenal medulla
- less problems
- secretes E and NE which target most cells and activate the SD of the ANS
adrenal cortex
- most endocrine problems
- secrete 3 groups of hormones
what 3 groups of hormones does the adrenal cortex secrete?
1) Glucocorticoids (cortisol)
2) Mineralcorticoids (prednisone, cortisone)
3) Gonadocorticoids (androgens)
Glucorticoids
- secreted in response to stress
- target most cells to decrease inflmtn
- alters metabolism of proteins and fats
- suppresses immune response
Mineralcorticoids
-targets kidneys to increase Na+ reabsorption, which increases fluid retention and increases blood volume and pressure
Gonadocorticoids
- androgens are male sex hormones (testosterone)
- very small amount released from adrenal glands (in men and women), but most is prod in testes
- excess of andorgens prod by male may not be affected, while female will develop secondary male sex characteristics
ACTH
- produced?
- released?
- function?
- prod and released by ant pit
- stimulates cortex to release cortisol
cortical tumor or hyperplasia
excessive cortisol prod, and decreased ACTH (in a - feedback loop)
when would hypersecretion occur?
if there are more cells to secrete these hormones
pituitary tumor or hyperplasia
excessive ACTH prod resulting in excessive cortisol prod
ectopic tumors
in a location in the body that isn’t a gland, but does the same fx as that gland
example of ectopic tumor
- malignancy in lung produces ACTH-like substance which stimulates cortisol prod.
- when negative feedback loop suppresses ACTH d/t high amount of cortisol, the substance isn’t affected = cortisol keeps rising