Basic Concepts on Laboratory Biosafety and Biosecurity

Question 1

Individuals who handle and process microbiological specimens are vulnerable to pathogenic microorganisms which are possible
sources of

Answer 1

Laboratory acquired infections

Question 2

Laboratory biosafety and biosecurity traces its history in

Answer 2

North America and Western Europe

Question 3

The origins of biosafety were rooted in

Answer 3

US biological weapons program

Question 4

was designated a permanent installation for biological research and development

Answer 4

Camp detrick

Question 5

engaged some of Camp Detrick’s leading scientist
about the nature of their work and developed specifically technical solutions such as Class III safety cabinets and laminar flow hoods to address specific risks

Answer 5

Newell Johnson

Question 6

What does ABSA stand for

Answer 6

American biological biosafety program

Question 7

Describe the use of mechanical pipettors to
prevent laboratory-acquired infections in 1907 and 1908

Answer 7

Arnold Wedum

Question 8

Early progenitors to the nearly ubiquitous engineered control now known as the
biological safety cabinet, were also first documented outside of the US biological weapons programs

Answer 8

Ventilated cabinets

Question 9

What does CDC Stand for

Answer 9

Center for disease control

Question 10

What does SRCVB VECTOR stand for

Answer 10

State Research Center of
Virology and biotechnology
VECTOR (SRCVB VECTOR)

Question 11

introduced the concept of
establishing ascending levels of
containment associated with risks in
handling groups of infectious
microorganisms that present similar
characteristics

Answer 11

Classification of Etiological Agents on the Basis of Hazard,

Question 12

It explained in detail the microbiological practices,
equipment, and facility necessarily corresponding to four ascending levels of physical containment

Answer 12

Guidelines for Research Involving Recombinant DNA Molecules

Question 13

The technical means of mitigating the risk of
accidental infection from or release of agents in the laboratory setting as well as the community and environment it is situated in

Answer 13

Biosafety levels

Question 14

Analyzed multiple epidemiological studies of
laboratory-based outbreaks

Answer 14

Arnold Wedum and Morton Reitman

Question 15

to monitor the transfer of a select list of biological agents from one facility to another.

Answer 15

Select agent regulations

Question 16

materials that pose the greatest risk of
deliberate misuse, and the remaining select agents.

Answer 16

Tier 1 agents

Question 17

similar in scope with the US regulations but with more severe penalties for noncompliance

Answer 17

Singapore’s Biological Agents and Toxins Act

Question 18

amended to require institutions that work with
listed “highly dangerous pathogens” to implement
laboratory biosafety and biosecurity requirements to prevent the loss, theft, diversion, release,or misuse of these agents

Answer 18

Act on Prevention of Infectious Diseases in 2005

Question 19

To address concerns on biosafety guidance for research and health laboratories, issues On risk
assessment and guidance to commission and certified laboratories

Answer 19

3rd edition of the Laboratory Biosafety Manual

Question 20

to ensure “an adequate level of protection in the field of safe transfer, handling, and use of living
modified organisms (LMOS) resulting from modern
biotechnology.”

Answer 20

Cartagena Protocol on Biosafety (CPB)

Question 21

established under E.O. 430 series of
1990, it focuses on the organizational
structure for biosafety: procedures for evaluation of proposals with biosafety concerns; procedures and guidelines on the introduction, movement, and field release of regulated materials; procedures on physico-chemical and biological containment

Answer 21

National Committee on Biosafety of the Philippines (NCBP)

Question 22

to set in place policies on the importation and release. of plants and plant products derived from
modern biotechnology.

Answer 22

Department of Agriculture (DA)also issued Administrative Order No. 8

Question 23

formulated guidelines in the assessment of the impacts on health posed by modern biotechnology and its applications

Answer 23

Department of Health (DOH) together with NCBP

Question 23

formulated guidelines in the assessment of the impacts on health posed by modern biotechnology and its applications

Answer 23

Department of Health (DOH) together with NCBP

Question 24

Founded in 2005, Acts as a professional society for
biosafety professionals in the Asia-Pacific region. Its members are from Singapore, Brunei, China, Indonesia, Malaysia, Thailand, the Philippines and
Myanmar. Active members of the International
Biosafety Working Groups are required to directly contribute to the development of the best biosafety practices.

Answer 24

ASIA-PACIFIC BIOSAFETY ASSOCIATION (A-PBA)

Question 25

Aims to provide a forum for discussions and debates on issues of concern and to represent those working in the field of biosafety. Founded in June 1996

Answer 25

European Biological Safety Association
(EBSA)

Question 26

Created by a multidisciplinary team with members coming from the health and education sectors as well as individuals from the executive, legislative, and judicial branches of the government

Answer 26

Philippine Biosafety and Biosecurity Association

Question 27

Containment principles, technologies
and practices that are implemented
to prevent unintentional exposure to
pathogens and toxins, or their
accidental release.

Answer 27

Biosafety

Question 28

The protection, control and
accountability for valuable biological
materials within laboratories in order
to prevent their unauthorized
access, loss, theft, misuse,
diversion, or intentional release

Answer 28

Biosecurity

Question 29

Created the BIOHAZARD SYMBOL
used in labeling biological materials
carrying significant health risks

Answer 29

Charles Baldwin

Question 30

includes microorganisms that are
unlikely to cause human or animal
disease. low individual and community risk

Answer 30

Risk Group 1 (No or Low individual and
community risk)

Question 31

includes microorganisms that are
unlikely to be a significant risk to
laboratory workers and the
community, livestock, or the
environment. Laboratory exposure may cause
infection, however, effective
treatment and preventive measures
are available. While the risk of spread is limited,
this risk group brings about moderate
individual risk and limited community
risk

Answer 31

Risk Group 2 (Moderate Individual Risk,
Low community Risk)

Question 32

includes microorganisms that are
known to cause serious diseases to
humans or animals and may present
a significant risk to laboratory
workers. Could present a limited to moderate
risk if these microorganisms spread
in the community or the environment. There are usually effective preventive
measures or treatment available. High individual risk and limited to moderate community risk

Answer 32

Risk Group 3 (high individual risk, low community risk)

Question 33

microorganisms that are known to
produce Life-threatening diseases to
humans or animals. It represents a significant risk to laboratory workers. May be readily transmissible from one individual to another. Effective treatment and preventive
measures are not usually available

Answer 33

Risk Group 4 (high individual and
community risk)

Question 34

suitable for work involving viable
microorganisms that are defined and
with well-characterized strains
known not to cause disease in
humans.

Answer 34

Biosafety level 1

Question 35

For laboratories that deal with
indigenous moderate-risk agents
present in the community. All procedures where infectious aerosols or splashes may be created
are conducted in biosafety cabinets
or other physical containment
equipment.

Answer 35

Biosafety level 2

Question 36

Emphasis on primary and secondary
barriers in the protection of the
personnel, the community, and the
environment from infectious aerosol
exposure. Work With indigenous or exotic
agents with a potential for
respiratory transmission, and that
may cause serious and potentially
lethal infection are being conducted
here

Answer 36

Biosafety level 3

Question 37

dangerous and exotic agents that pose high individual risks of life- threatening diseases that may be transmitted via the aerosol route. The laboratory worker’s complete
isolation from aerosolized infectious
materials is accomplished primarily
by working in a Class III biosafety
cabinet or in a full-body air-supplied
positive-pressure personnel suit.

Answer 37

Biosafety level 4