Basic Concepts of Hematology Flashcards

1
Q

Study of diseases of blood, concentration, morphology and function, precursor of blood cells

A

Hematology

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2
Q

Cessation of bleeding

A

Hemostasis

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3
Q

Thrombosis is a process of

A

Clot formation

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4
Q

In 1657, He describes “worms” in blood7

A

Athanasius Kircher

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5
Q

In 1674, He discovered RBC by using the microscope

A

Anton Van Leeuwenhoek

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6
Q

He described platelet as ‘petite plaques’

A

Guilio Bizzozero

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7
Q

Blood composition that is composed of
- Erythrocytes
- Plateletes
- Leukocytes
- Plasma

A

Whole Blood

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8
Q

White small layer; w/ packed cell volume and plasma

A

Buffy coat

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9
Q

Plasma is composed of

A

Leukocytes and Platelets

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10
Q

Fluid by which blood is allowed to clot

A

Serum

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11
Q

Serum appears to be

A

Clear and straw

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12
Q

Fluid by which blood is not clotted

A

Plasma

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13
Q

Plasma appears to be

A

Hazy with yellow pale color

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14
Q

Percentage of blood in the body

A

8%

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15
Q

Percentage of packed cell volume

A

45%

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16
Q

Percentage of Plasma

A

55%

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17
Q

Estimated count of Platelets in the body

A

200-400k

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18
Q

Estimated count of WBC in the body

A

5-9k WBC

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19
Q

Estimated count of RBC in the body

A

4.2 - 6.2 Million

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20
Q

Percentage of Neutrophils

A

60-70%

21
Q

Percentage of Lymphocytes

A

20-25%

22
Q

Percentage of Monocytes

A

3-8%

23
Q

Circulatory system is made up of

A

Blood
Heart
Blood vessels

24
Q

carry HIGH oxygenated blood FROM HEART TO THE BODY

A

Arteries

25
Q

carry LOW oxygenated blood FROM BODY TO HEART

A

Veins

26
Q

Connects arteries and capillaries

A

Arterioles

27
Q

Connects Veins and Capillaries

A

Venules

28
Q

connects arterioles and venules; Transport blood, nutrients, and oxygen

A

Capillaries

29
Q

Single layer of cell, lines up blood vessel
SITE OF COLLAGEN FORMATION

A

Endothelium

30
Q

Functions of Hematology Laboratory

A
  • Diagnosis/ruling out of disease
  • Confirms clinical impressions of possible hematological disorder
  • Detects unsuspected disease
  • Monitor effect of therapy
  • Detects minimal residual disease
31
Q

Standard Precautions is required by

A

OSHA

32
Q

Most common site for venipuncture

A

Superficial veins of ANTECUBITAL FOSSA

33
Q

Blood collection method used for newborn, pediatric, geriatic

A

Skin puncture

34
Q

Under 1 year of age site of skin puncture

A

lateral/medial PLANTAR surface of heel

35
Q

Children >1 year of age

A

Palmar surface distal position, 3rd/4th digits

36
Q

Difference of Capillary blood and venous blood

A

Capillary blood has more Glucose (10-20 mg/dL) and leukocytes (1000 uL) but less RBC, hemoglobin, and Platelets than venous.

RBC in Capillary is more fragile

37
Q

3 categories of blood cells

A

Red blood cell
White Blood cell
Platelets

38
Q

Size of RBC

A

6-8 um with 1/3 central pallor

39
Q

Anucleate, biconcave, discoid

A

RBC

40
Q

Insufficient amount of blood volume

A

Anemia

41
Q

Increase amount of RBC in the body

A

Polycythemia vera

42
Q

Cells that protect host from infections

A

WBC

43
Q

Decreased amount of WBC

A

Leukopenia

44
Q

Increased amount of WBC

A

Leukocytosis

45
Q

decreased amount of all cell

A

Leukemia

46
Q

3rd line of defense are

A

NK cells, Plasma, Macrophage

47
Q

cells that maintains the intergrity of blood vessel

A

Platelets

48
Q

Accumulation of aggregation

A

White thrombus