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Virology > Basic charts > Flashcards

Basic charts Flashcards

0
Q

Coronavirus

A

Genome: +RNA
Polymerase? No
Capsid: helical
Envelope? Yes

Incubation: 2-10 days
Viremia? No
Transmission: Respiratory
Vaccine: No

Includes: cold, SARS, MERS

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1
Q

Picornavirus

A

Genome: +RNA
Polymerase? No
Capsid: icosahedral
Envelope? No

Transmission: fecal-oral (Rhino airborne)
Incubation: polio 2-3 weeks, Hep A 30 days
Viremia? Yes
Vaccine:
- Hep A killed
- Polio killed (Salk), attenuated (Sabin)

Includes:

  • Entero - polio, Coxsackie, Echo, numbered (Hep A)
  • Rhino
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2
Q

Togavirus

A

Genome: +RNA
Polymerase? No
Capsid: Icosahedral
Envelope? Yes

Incubation: Arbo (7 days), Rubella (18 days)
Viremia? Yes
Transmission: Arbo - mosquitoes, Rubella airborne
Vaccine: Rubella live attenuated

Includes:

  • Arbo - Eastern and Western equine
  • Rubella
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3
Q

Flavivirus

A

Genome: ss +RNA
Polymerase? No
Capsid: Icosahedral
Envelope? Yes

Incubation: Arbo - 7 days, Hep C - 60 days (insidious)
Viremia? Yes
Transmission: Arbo - arthropod, Hep C - blood, perinatal, sex
Vaccine:
- yellow fever - attenuated
- Japanese encephalitis - killed

Includes:

  • Arbo - St Louis, West Nile, Japanese, yellow fever, Dengue
  • Hepaci - Hep C
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4
Q

Orthomyxo

A

Genome: segmented ss (-)RNA (8 segments)
Polymerase? RNA-dep RNA
Capsid: helical
Envelope? Yes

Incubation: 3-6 days
Viremia? uncommon
Transmission: airborne
Vaccine: 
 - killed (IM) trivalent
 - attenuated (intranasal) quadrivalent

Includes:
- Influenza (A, B, C)

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5
Q

Paramyxo

A

Genome: single ss (-)RNA
Polymerase? RNA-dep RNA
Capsid: helical
Envelope? Yes

Incubation: Mumps 18-21 days, measles 14 days
Viremia? Yes
Transmission: airborne
Vaccine: live attenuated (measles, mumps)

Includes:

  • parainfluenza (1-4)
  • RSV
  • measles
  • mumps
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6
Q

Rhabdovirus

A

Genome: single ss(-)RNA
Polymerase? RNA-dep RNA
Capsid: Helical
Envelope? Yes

Incubation: weeks-months
Viremia? No (travel through neurons)
Transmission: Bite
Vaccine:
 - killed - preventative
 - post-exposure -> killed + IgG (passive)

Includes:
- Rabies

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7
Q

Reovirus

A

Genome: segmented dsRNA
Polymerase? RNA-dep RNA
Capsid: Icosahedral
Envelope? No

Incubation: ?
Viremia? No?
Transmission: Fecal-oral
Vaccine: Live attenuated

Includes: Rotavirus

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8
Q

Retrovirus

A

Genome: x2 identical ss(+)RNA
Polymerase? RNA-dep DNA (reverse transcriptase)
Capsid: Icosahedral
Envelope? Yes

Incubation: long…weeks
Viremia? Yes
Transmission: blood, sex, perinatal, breastmilk
Vaccine: no

Includes:

  • Onco -> HTLV
  • Lenti -> HIV
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9
Q

Papovavirus

A

Genome: circular dsDNA
Polymerase? No
Capsid: Icosahedral
Envelope? No

Incubation: long?
Viremia? No
Transmission: contact
Vaccine:
 - Gardisil, Cervarix = killed

Includes:

  • HPV
  • SV40 (monkeys)
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10
Q

Adenovirus

A

Genome: linear ds DNA
Polymerase? No
Capsid: Icosahedral
Envelope? No

Incubation: 3-10 d
Viremia? 
Transmission: fecal-oral (enteric), aerosol
Vaccine:
 - live attenuated

Includes:
- enteric, wide range (conjunctivitis…)

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11
Q

Herpesvirus

A

Genome: single linear ds DNA
Polymerase? No
Capsid: Icosahedral
Envelope? Yes

Incubation: 1-2 weeks
Viremia? No (neural spread)
Transmission: Contact/Sex, perinatal
Vaccine: 
 - Varicella/zoster = live attenuated

Includes:
- HSV 1,2, CMV, Kaposi’s, EBV, Varicella/Zoster

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12
Q

Poxvirus

A

Genome: Linear dsDNA
Polymerase? DNA-dep RNA
Capsid: Brick…assymetrical
Envelope? Two forms - both enveloped and unenveloped

Incubation: 2-8 weeks
Viremia? Yes (two phases)
Transmission: Oral -> aerosol, direct contact
Vaccine:
  vaccinia - live attenuated

Includes:

  • smallpox
  • molluscum contagiosum
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13
Q

Hepadnavirus

A

Genome: circular ds DNA with some single portions
Polymerase? RNA-dep DNA (reverse transcriptase)
Capsid: Icosahedral
Envelope? Yes

Incubation: 70 days (insidious)
Viremia? Yes
Transmission: Blood, Sex, Perinatal
Vaccine:
 - subunit

Includes:
- Hep B

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14
Q

Parvovirus

A

Genome: ssDNA
Polymerase? No
Capsid: Icosahedral
Envelope? No

Incubation: 14 d
Viremia? Yes
Transmission: Respiratory, transplacental
Vaccine: No

Includes:
- Parvovirus B19

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15
Q

Respiratory transmission

A 
Rhino
Influenza
Parainfluenza
Measles
Mumps
Rubella
Varicella
Smallpox
Adeno
Parvovirus
16
Q

GI transmission

A 
Polio
ECHO
Coxsackie
Adeno (enteric)
Hep A
Hep E
Rotavirus
17
Q

Direct contact transmission

A

HSV
HPV
Molluscum contagiosum

18
Q

Venereal transmission

A

Hep B, C, D
HSV (2)
HIV
HPV

19
Q

Transplacental

A 
Rubella
CMV
Varicella
HIV
Parvo B19
20
Q

Perinatal transmission

A

vs transplacental…

HSV
HIV
Hep B, C, D

21
Q

Breastfeeding transmission

A

HIV

CMV

22
Q

Blood transmission

A

HIV

Hep B, C, D

Virology (16 decks)

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