Basic Bacteriology Flashcards

1
Q

disease without colonizations occur because of

A

toxins

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2
Q

when bacteria transition from harmless to aggressive based upon population density

A

quorum sensing

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3
Q

what us the prodrome phase

A

when you start to have mild symptoms

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4
Q

what is the acme phase

A

symptoms peak

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5
Q

what is convalescence

A

healing

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6
Q

what is the pili used for

A

attachment and sex

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7
Q

what does the plasmid DNA do

A

toxins and antibiotic resistance

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8
Q

what kind of bacteria has LPS in the outer membrane

A

gram negative

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9
Q

LPS is an example of an _______

A

endotoxin

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10
Q

what is the enzyme that catalyszes the crosslink to form peptidioglycan

A

transpeptidase

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11
Q

what antibiotic binds and inhibits transpeptidase

A

penicillin

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12
Q

what are the two sugars that compose peptidoglycan

A

NAG and NAM

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13
Q

what type of bacteria have porin channels

A

gram negative

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14
Q

what type of bacteria are vulnerable to lysozyme and penicillin attack

A

gram posititve

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15
Q

Gram positive capsules are composed of

A

teichoic acid

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16
Q

what are the three components of a lpopolysaccharide

A
  1. O antigen
  2. core polysaccharide
  3. inner lipid A (inflammatory)
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17
Q

LOS is found on what bacteria

A

Nisseria (not LPS)

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18
Q

LOS is the equivalent of

A

LPS

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19
Q

what are the physiological response to endotoxin

A

inflammation, fever, and shock

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20
Q

what is a component of LPS released by lysis of GNRs anf on GPR

A

endotoxin (LIPID A)

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21
Q

what is bacteria in the blood called

A

bacteremia

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22
Q

what is sepsis

A

organ dysfunction

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23
Q

what are the three indications of sepsis

A
  1. altered mental state
  2. tachypnea (>22 bpm)
  3. low SBP (<100 mmHG)
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24
Q

if the qSOFA is less than two, what is suspected? what if more than one?

A

simple infection; sepsis

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25
Q

bacteria’s flagella is made out of ______, while eukaryotes flagella is made out of ________.

A

flagellin; tubulin

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26
Q

what are the key spore formers?

A

ABC

  1. actinomyces
  2. bacillus
  3. clostridium
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27
Q

bacteria that prefer oxygen, but can live anaerobically

A

faculatative anaerobe

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28
Q

listeria, yersinia, and aeromonas like

A

cold. cold. cool

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29
Q

campylobacter likes it

A

hot

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30
Q

if a gram us positive, aerobic cultures are _______

A

negative

31
Q

require low oxygen and high carbon dioxide

A

apnophiles

32
Q

are synthesized and pumped out of bacteria

A

exotoxins

33
Q

enterotxins are exotoxins found in the

A

gut

34
Q

what does TLR-2 recognize

A

peptidoglycan

35
Q

what does TLR-4/CD14 recognize

A

LPS

36
Q

what does TLR-5 recognize

A

flagellin

37
Q

how do phagocytes kill things

A

ROS and NO

38
Q

What are the strict aerobes

A

NPMB

Norcadia, pseudomonas, mycobacteria, bacillus

39
Q

What are the strict anaerobes

A

FCBA

Fusobacterium, clostridium, bacteroid, actinomyces

40
Q

What do siderophores do

A

Transport iron

41
Q

How do enterotoxins cause diarrhea

A

Inhibit NaCl resorption, activate NaCl secretion, kill intestinal/epithelial cells-> promotes osmotic flow to gut

42
Q

What are the strict aerobes

A

NPMB

Norcadia, pseudomonas, mycobacteria, bacillus

43
Q

What are the strict anaerobes

A

FCBA

Fusobacterium, clostridium, bacteroid, actinomyces

44
Q

What do siderophores do

A

Transport iron

45
Q

How do enterotoxins cause diarrhea

A

Inhibit NaCl resorption, activate NaCl secretion, kill intestinal/epithelial cells-> promotes osmotic flow to gut

46
Q

What are the strict aerobes

A

NPMB

Norcadia, pseudomonas, mycobacteria, bacillus

47
Q

What are the strict anaerobes

A

FCBA

Fusobacterium, clostridium, bacteroid, actinomyces

48
Q

What do siderophores do

A

Transport iron

49
Q

How do enterotoxins cause diarrhea

A

Inhibit NaCl resorption, activate NaCl secretion, kill intestinal/epithelial cells-> promotes osmotic flow to gut

50
Q

What are the strict aerobes

A

NPMB

Norcadia, pseudomonas, mycobacteria, bacillus

51
Q

What are the strict anaerobes

A

FCBA

Fusobacterium, clostridium, bacteroid, actinomyces

52
Q

What do siderophores do

A

Transport iron

53
Q

How do enterotoxins cause diarrhea

A

Inhibit NaCl resorption, activate NaCl secretion, kill intestinal/epithelial cells-> promotes osmotic flow to gut

54
Q

What are the strict aerobes

A

NPMB

Norcadia, pseudomonas, mycobacteria, bacillus

55
Q

What are the strict anaerobes

A

FCBA

Fusobacterium, clostridium, bacteroid, actinomyces

56
Q

What do siderophores do

A

Transport iron

57
Q

How do enterotoxins cause diarrhea

A

Inhibit NaCl resorption, activate NaCl secretion, kill intestinal/epithelial cells-> promotes osmotic flow to gut

58
Q

What are the strict aerobes

A

NPMB

Norcadia, pseudomonas, mycobacteria, bacillus

59
Q

What are the strict anaerobes

A

FCBA

Fusobacterium, clostridium, bacteroid, actinomyces

60
Q

What do siderophores do

A

Transport iron

61
Q

How do enterotoxins cause diarrhea

A

Inhibit NaCl resorption, activate NaCl secretion, kill intestinal/epithelial cells-> promotes osmotic flow to gut

62
Q

What are the strict aerobes

A

NPMB

Norcadia, pseudomonas, mycobacteria, bacillus

63
Q

What are the strict anaerobes

A

FCBA

Fusobacterium, clostridium, bacteroid, actinomyces

64
Q

What do siderophores do

A

Transport iron

65
Q

How do enterotoxins cause diarrhea

A

Inhibit NaCl resorption, activate NaCl secretion, kill intestinal/epithelial cells-> promotes osmotic flow to gut

66
Q

What are the strict aerobes

A

NPMB

Norcadia, pseudomonas, mycobacteria, bacillus

67
Q

What are the strict anaerobes

A

FCBA

Fusobacterium, clostridium, bacteroid, actinomyces

68
Q

What do siderophores do

A

Transport iron

69
Q

How do enterotoxins cause diarrhea

A

Inhibit NaCl resorption, activate NaCl secretion, kill intestinal/epithelial cells-> promotes osmotic flow to gut

70
Q

What are the strict aerobes

A

NPMB

Norcadia, pseudomonas, mycobacteria, bacillus

71
Q

What are the strict anaerobes

A

FCBA

Fusobacterium, clostridium, bacteroid, actinomyces

72
Q

What do siderophores do

A

Transport iron

73
Q

How do enterotoxins cause diarrhea

A

Inhibit NaCl resorption, activate NaCl secretion, kill intestinal/epithelial cells-> promotes osmotic flow to gut