Bacterial Targets for Therapy

Question 1

Major bacterial targets for antibiotics

Answer 1

1. Cell wall synthesis
2. Plasma membrane integrity
3. Nucleic acid synthesis
4. Ribosomal function
5. Folate synthesis

Question 2

Antibiotics which affect cell wall synthesis

Answer 2

beta lactam

glycopeptide

Question 3

Antibiotics that inhibit protein synthesis

Answer 3

macrolides
tetracyclines
aminoglycosides
rifamycins

Question 4

Antibiotics which affect DNA synthesis/replication

Answer 4

nucleotide synthesis - sulphonamides and trimethoprim

DNA gyrase inhibition - quinolones