Bacterial Properties Flashcards
What are bacteria?
Small unicellular prokaryotes
Describe Bacterial DNA:
Haploid w/circular DNA chromosome
Do bacteria have a cell wall?
Yes
What does Gram stain bind to?
Peptidoglycan in cell walls
What are beneficial bacteria called?
Commensal
Name 5 Gram negative bacteria and the diseases they cause:
Escherichia Coli (EPEC -diarrhea, EHEC -dysentry)
Salmonella (typhimurium - food poisoning)
Shigella (Dysentry)
Vibrio cholerae (Cholera)
Neisseria (menningitidus - meningitis. gonorrhoeae - gonorrhea)
Name 3 Gram positive bacteria and the diseases they cause:
Staphylococcus aureus (pneumonia, endocarditis)
Streptococcus pneumoniae (pneumonia, meningitis, otitis media)
Streptococcus pyogenes (tonsilitis, necrotising fasciitis)
Name 2 mycobacteria and the diseases they cause:
Mycobacterium tuberculosis (TB)
Mycobacterium leprae (Leprosy)
What are the 2 locations a bacterial pathogen can replicate in a host?
Extracellular: S. aureus/Strep, neisseria
Intracellular: Listeria, Shigella, Salmonella, Mycobacteria
How do Salmonella and mycobacteria survive inside cells?
Present lysosome fusion
What do some bacteria use to inject virulence proteins into cells?
Injectisome; translocase complex creates pore in host cell
What is vertical transmission?
Binary fission: bacterial replication resulting in inheritance of identical CircDNA
What are the three methods of horizontal gene transfer?
Transformation
Conjugation
Transduction
What is transformation?
[horizontal transfer]
DNA uptake proteins incorperate DNA released from other sources into genome
What is Conjuative transfer?
Mating bridge forms and plasmid replicated and transferred