BACTERIAL INFX Flashcards
Skin lesions induced by Gram + staph usually appear as (3)
Pustules, furuncles, honey-colored crusts
- bullae, erythema, desquamation, vegetating pyodermas can also be due to gram staph
Two distinctive cutaneous lesions that occur with endocarditis
janeway lesion, osler nodes
Painful, erythematous nodule with a pale center lcoated on the fingertips
osler nodes
nontender, angular hemorrhagic lesions of the soles and palms
janeway lesion
phage type that causes majority of impetigo
types 71 or 55
term used to encompass vesicles that might be from a staphylococcal, strep, or combined infection
- characterized by discrete, thin-walled vesicles that rapidly become pustular and then rupture
impetigo contagiosa
group A beta hemolytic strep skin infection maybe followed by ___. Important factor predisposing to this disease are the ff serotype of strep (5)
- AGN
- Type 49, 55, 57, 60, M-type 2
It is a superficial folliculitis with thin-wall posters at the follicle orifices
superficial pustural folliculitis (impetigo of bockhart)
It is a perifollicular, chronic, pusutular staph infection of the bearded region characterized by inflammatory papules and pustules, and a tendency to recur
sycosis vulgaris aka barber’s itch
It is an uncommon chronic indolent disorder characterized by nodular, crusted, purulent lesions and sinuses that discharge sulfure granules.
- heals with atropic scars
botryomycosis
Most frequent site in tropical disease of pyomyositis is the ___ where as in HIV patients the ____ is most often involved followed closely by the ____
thigh
- deltoid, quadriceps
It is a generalized confluence superficially exfoliative disease occurring most often in neonates and children under five years old
SSSS
How will you differentiate SSSS from SJS/TEN
involvement of mucouse membrane in sjs/ten
- sjs/ten - skin separates at DEJ
- ssss - granular layer
What causes SSSS
Exotoxin type A and B
It is an acute febrile multi system illness with one of its major diagnostic criteria being a widespread macular erythematous eruption.
toxic shock syndrome
Toxin that causes toxic shock syndrome
TSST-1
CDC case def of TSS
-temp >38.9
-erythematous eruption
-desquamation of palms and soles 1-2 wks after onset
- hypotension
- involvement of 3 or more other systems (GI, muscular, mucosa, renal, haptic, hematologic, CNS)
- negative test for rocky mountain, lepto, rubeola
- negative culture of blood, urine, and CSF
It is an ulcerative strep or less commonly staph pyoderma.
-the disease begins with a vesicle or vesicopustule which enlargest and in a few days become thickly crusted
Ecthyma
a diffuse, erythematous exanthem that occurs during the course of strep pharyngitis
- it affects primarily children who developed the eruption 24 to 48 hours after onset of pharyngeal symptoms
Scarlet fever
Symptoms of scarlet fever
Tonsils are red and edematous, covered with exudate
-strawberry tongue with white coating (compared to kawasaki, no exudate)
-cutaneous eruption begins on the neck, then trunk, then ext.
- pastia’s lines - accentuation over the skin fold and a linear but he kill it option
Pathogen that causes starlet fever
GAS
acute beta-hemolytic Gas infx of the skin involving the superficial dermal lympathics
erisypelas/st.anthony’s fire
delayed nonsuppurative sequelae of strep infection includes (3)
erythema nodosum, psgn, rf (only after pharyngitis or tonsillitis)
Appears as a spreading patchy erythema that migrates peripherally and often forms polycyclic configurations
erythema marginatum
It is characterized by sharply delineated dry brown slightly scaling patches occurring in the intertriginous areas. (axilla genitocrural creases, webs between the fourth and fifth toes)
Erythrasma
Causative agent for erythrasma
Corynebacterium minitissimum
Corynebacterium triad
erythrasma, pitted keratolysis, trichomycosis
Diagnosis of erythrasma
wood’s light - coral red fluorescence
tender ulcer, painful inguinal adenitis that may suppurate
chancroid
causative agent of chancroid
H. ducreyi
DOC for chandroid
azith 1g po
ceftri 250mg im
erythromycin 500mg qid x 7d
cipro 500mg bid x 3d
mildly contagious, chronic, granulomatous, locally destructive disease characterized by progressive, indolent, serpingious ulcerations of the groins, pubes, genitalia, and anus
- no lymphadenopathy
granuloma inguinale/donovanosis/granuloma venerum
causative agent of granuloma inguinale
k. granulomatis
TX for granuloma inguinale
Azith 1g once weekly x 3 weeks
Alt: TMP-SMX 1ds po, cipro 750mg po, doxy 100mg bid, erythro 500mg qid x 2 3 wks
suppurative inguinal adenitis with matted LNs, inguinal bubo with secondary ulceration and constitutional symptoms
LGV
Due to separation of enlarged inguinal LN from femoral LN by the inguinal ligament seen in LGV
groove sign
causative agent of LGV
C. trachomatis
DOC for LGV
Doxy 100mg BID x 3 wks
alt: erythro 500mg QID x 21d
