Bacterial Cell Wall Flashcards
What are the major functions of the bacterial cell wall?
~Protection from osmotic changes.
~Determination and maintenance of cell shape.
BACTERIAL cell walls are made of
Peptidoglycan
Peptidoglycan has a
Polysaccharide portion and peptide portion
The polysaccharide is a complex
Polymer consisting of alternating monosaccharides called (NAG) and (NAM)
Gram-positive cell wall consist of
~Many layers of Peptidoglycan surrounding the plasma membrane
~tectonic acids and lipotechoic acids
The gram negative cell wall are
~More complex
~Consists of only a single of Peptidoglycan surrounding the plasma membrane and outer membrane
The outer membrane is phospholipid like the plasma membrane, but also contains
~Lipoprotein- which anchor it to the cell wall and plasma membrane
~Lipopolysaccharide (which contain Lipid A, an endotoxin, and O polysaccharide, an antigen)
~Porin proteins- allows transport of small hydrophilic molecules across the outer membrane
Outer membrane structures and functions
~Protects cell by excluding large toxic molecules
~Creates a periplasmic space
~No techoic acids
Gram-negative cell walls
~are susceptible to mechanical breakage that gram-positive ones
~are more successful in avoiding poor osmotic conditions.
Cell walls can be damaged by
~Lysozyme-enzyme that breaks down glycosidic bonds between NAG and NAM
Penicillin-an antibiotic that interferes with the cell wall synthesis by inhibiting peptide bridge formation p
Major functions of plasma membrane
~Delineates cell boundary, and hold in the contents
~To control transportation of substances into and out of the cell