Bacteria/antibiotics Flashcards

1
Q

Antibiotic

A

chemical substance that is produced by a MICROORGANISM and has the ability to inhibit growth or kill another microorganism

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2
Q

Antimicrobial

A

Any substance, natural, synthetic, semi-synthetic (not from a microorganism) that inhibits the growth or kills a microorganism

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3
Q

Therapeutic use

A

when diseased animals are treated to cure infection

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4
Q

Prophylactic use

A

when healthy herd or animals are treated to prevent infection

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5
Q

Metaphylactic use

A

when diseased herds are treated to cure infection in some animals and prevent infection in others

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6
Q

Growth promotional use

A

When healthy animals are treated with low concentrations to improve growth, reproductive performance etc

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7
Q

Beta-lactams

A

Penicillins
Cephalosporins
Carbapenems**

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8
Q

Penicillins

A

Penicillin G
Ampicillin/amoxicyllin
Amoxicillin/clavulanic acid

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9
Q

Cephalosporins

A

Cefalexin/cephadroxil

“Cefs”

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10
Q

Carbapenems**

A

Imipenem/meropenem

Entrapenem/Doripenem

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11
Q

Tetracyclines

A

Tetracycline
Oxytetracycline
Doxycycline

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12
Q

Quinolones

A

Oxolinic acid
Enrofloxacin/marbofloxacin
paradofloxacin/norfloxacin

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13
Q

Sulfonamides

A

Sulfadiazine

Trimethoprim

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14
Q

Phenicols

A

Chloramphenicol

Florfenicol

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15
Q

Macrolides

A

Erythromycin

Tiamulin/tilmicosin

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16
Q

Lincosamides

A

Lycomycin/Clindamycin

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17
Q

Aminoglycosides

A

Streptomycin
Gentamicin/Neomycin
Amikacin

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18
Q

Polypeptides

A

Colisitin/polymixin

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19
Q

Metronidazole

A

.

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20
Q

Glycopeptides*

A

Vancomycin/Teicoplanin

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21
Q

Oxazolidinones*

A

Linexolide

22
Q

Examples of ANTIBIOTICS

A
Aminoglycosides
Cephalosporins
Actinomycetes
Penicillins
Phenicols
Rifamycins
Tetracyclines
23
Q

Bactericidal

A

Kills

24
Q

Bacteriostatic

A

inhibits growth

25
Q

Bactericidal Drugs

A
Aminoglycosides
Cephalosporins
Glycopeptides
Penicillins
Quinolones
Rifamycins
26
Q

Bacteriostatic Drugs

A
Lincosamids
Macrolides
Phenicols
Sulfonamides
Tetracyclines
27
Q

Penicillin spectrum

A

Best on gram positive and anaerobes

-some gram negative

28
Q

Cephalosporin spectrum

A
  • Gram negative
  • Gram positive
  • some anaerobes
29
Q

Aminoglycosides spectrum

A
  • Gram positive

- some gram positive

30
Q

Tetracycline spectrum

A
  • Ehrlichia
  • Rickettsia
  • Chalmydia
31
Q

Flouroquinolone spectrum

A

ALL

32
Q

Glicopeptides spectrum

A

Gram-positive

33
Q

Macrolides spectrum

A
  • Gram positive

- Some Gram negative

34
Q

Lincosamides spectrum

A
  • Gram positive
  • Most anaerobes
  • Some gram negative
35
Q

Polymixin spectrum

A

Gram-negative

36
Q

Metronidazole spectrum

A

Anaerobes

37
Q

Drugs active against Gram + cocci

A
Best
-Penicillins
-Aminopenicillins
-Amoxicillin/clavulanate
-Cephalosporins
Bad
-Metronidazole
38
Q

Drugs active against penicillase- producing straphylococci

A
Best
-Amoxicillin/clavulanate
-Cephalosporins
-Flouroquinolones
Bad
-Penicillins
-Aminopenicillins
-Metronidazole
-Aminoglycosides
39
Q

Drugs active against Gram negative rods

A
Best
-Amoxicillin/clavulanate
-Cephalosporins (3/4gen)
-Flouroquinolones
-Aminoglycosides
Bad
-Metronidazole
-Penicillins
-Lincosamides
-Macrolides
40
Q

Drugs active agains anaerobes

A
Best
-penicillins
-aminopenicillins
-Lincosamides
-Metronidazole
-Amoxicillin/clavulanate
Bad
-Flouroquinolones
-Aminoglycosides
41
Q

Cell wall synthesis inhibitors

A
Cycloserine
Vancomycin
Bacitracin
Penicillins
Cephalosporins
Monobactams
Carbapenems
42
Q

Folic Acid metabolism

A

Trimethoprim

Sulfonamides

43
Q

Cytoplasmic Membrane structure

A

Polymixins

Daptomycin

44
Q

DNA gyrase

A

Quinolones

  • Nalidixic acid
  • Ciprofloxacin
  • Novobiocin
45
Q

RNA elongation

A

Actinomycin

46
Q

DNA-directed RNA polymerase

A

RIfampin

Streptovaricins

47
Q

50s inhibitors

A

Erythromycin
Chloramphenicol
Clindamycin
Lincomycin

48
Q

30s inhibitors

A
Tetracycline
Spectinomycin
Streptomycin
Gentamicin
Kanamycin
Amikacin
Nitrofurans
49
Q

Protein Synthesis (tRNA)

A

Mupirocin

Puomycin

50
Q

Time dependent Drugs

A
Penicillins
Cephalosporins
Macrolides
Lincosamides
Tetracyclines
51
Q

Concentration dependent Drugs

A

Aminoglycosides

Flouroquinolones