Bacteria 5 Flashcards
Opportunist pathogens
do not cause disease in a healthy host, with a healthy immune system
True Pathogens
are equipped with virulence genes for adherence, invasion, evasion from the immune system and toxins
Nosocomial infections
hospital acquired infections
Staphylococcus aureus, Clostridium difficile
Obligate intracellular pathogen
need a cell to replicate.
Rickettsia
Facultative intracellular pathogen
can survive in extracellular and intracelluar locations
Mycobacteria
Mycoplasma
Cell wall deficient, bacteria do not have peptidoglycan.
Mycobacteria
have mycolic acid, and will stain postive for acid fast staining
Staphylococcus
skin and mucus membranes. pyogenic bacterial. abscesses and infections.
S. hyicus
Greasy Pig disease- staphylococcus
how to test for Staphylococcus
coagulase test, and SPA
check for enterotoxin A-E
MRSA
Nosocomial infection, methicillin resistant S. aureus
Streptococcus
have a capsule to help evade phagocytosis
S. pyogenes
Strept- humans
S. agalactiae & S. dysgalactiae
Mastitis
S. equi subsp. equi
Strangles in horses
Bacillus Anthracis
Gram Postive (Violet)
three toxins present
Anti-phagocytic
polymer of D-Glutamic acid
3 (tripartite toxin) proteins encoded in the plasmid for Anthrax
Edema Factor- calmoduline,inhibit neutrophil function
Lethal Factor- zinc, cell death
Protective Antigen-cell binding factor
Erysipelothrix Rhusiopathiae
Swine erysipelas
Diamond skin disease in swine
Corynebacterium pseudotuberculosis
Caseous lymphadenitis
Absess in lymph nodes. (goats)
Actinomyces Bovis
Lumpy jaw in cattle.
pyogranulomatous osteomyelitis
mycobacterium tuberculosis complex
Acid Fast Positive, mycolic acid.
Facultative intracellular bacteria. humans and cows
Johne’s Disease
M. avium. subsp paratuberculosis
Thick intestines, cannot absorb nutrients and become malnourished.
Listeria Monocytogenes
septicemia, abortion, meningoencephalitis
Facultatice intracellular bacterium
food borne,
use host actin filaments to travel in the cell
Clostridium
histotoxic, invasive. 6 types
Clostridium Tetani
infects surgical wounds, causes spastic paraylsis. Lock Jaw
Clostridium botulinum
Produce botulinum toxin, and causes flaccid paralysis. Intoxication with BoNT
Examples of Gram Negative Bacteria
Group Enterobacteriaceae-present in water, soil, and GI tract
Coliform Bacteria- E.coli, Klebsiella,Enterobacter. (coliform enumeration is used to evaluate fecal contamination in drinking water)
Escherichia coli
Neonatal Colisepticemia in calves
edema disease in pigs
hemorrhagic enteritis in humans
hemolystic uremic syndrome and kidney failure O157H7
Salmonella enterica
gastroenteritis and systemic diseases
dublin- cattle
typhi- humans
enteritidis- chickens
Actinobacillus pleuropneumoniae
Fibrinonecrotic pneumonia in pigs
Pasteurella Multocida and Mannheimmia hemolytica
Shipping Fever pneumonia in cattle
Brucellosis
Abortus, melitensis, suis. canis.
reproductive system and general illness, survive in macrophages, zoonotic disease
Bordetella Bronchiseptica
Kennel Cough in dogs
Atrophic Rhinitis in swine
Leptospirosis
Spirochete (endoflagella)
bacteria live in the kidney tubules.
widespread zoonotic disease
Borelia Burgdorferi
Spirochete, causes lyme disease. Tick Vector
Mollicutes- Mycoplasma
in humans- walking pneumonia
in cattle- pneumonia and arthritis.
no cell wall- no peptidoglycan
no gram staning and not susceptaible to penicillin
Fried Egg colony- smallest prokaryotic cells about to self replicate.
Rickettsiales
Obligate Intracellular bacteria. Transmittec though Ticks
also Anaplasma, and Ehrlichia