BACTE LEC Flashcards
entrance and
multiplication of a
microorganism in or on a host
INFECTION
an infection w/ functional and structural harm to the host that is usually accompanied
by signs and symptoms
INFECTIOUS DISEASE
presence and multiplication of new
microorganisms that may cause an infectious disease or eliminated by host defenses
COLONIZATION
a microbe capable of
causing a disease
PATHOgen
study of the structural and functional manifestations of a disease
PATHOlogy
a physician specializing in
pathology
PATHOlogist
the ability to cause a
disease by overcoming host’s defenses
PATHOgenicity
steps or mechanisms
involved in the development of a disease; disease process
PATHOgenesis
degree of pathogenicity
Virulence
study of the cause/s of disease
Etiology
environment or place of
origin of the infecting agent
Reservoir
*Quantitative measure of pathogenicity
*Measured by the number of organisms required to
cause disease
VIRULENCE
number of
organisms needed to kill half of the
hosts/population.
50% of lethal dose (LD50)
number of organisms needed to cause infection in half the hosts/population.
- ID of Shigella is less than 100
- ID of Salmonella is about 100,000
50% of infectious dose (ID50)
*Acquired in the HOSPITAL or other health care settings
*Causative agent is not present and not incubating in the patient on entry or admission into the health care facility
Ex.
UTIs, Surgical wound
infections LR infections,
bacteremia
NOSOCOMIAL INFECTION