Background Flashcards

1
Q

What is heterotopic ossification (HO)?

A

HO refers to abnl lamellar bone formation in nonosseous tissues such as muscles, nerves and connective tissue. It often appears after trauma or Sg in periarticular ST and is commonly associated with injury to the hip.

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2
Q

What are common Sx of HO?

A

In HO, functional impairment such as joint stiffness and decreased ROM are the most common Sx. Pain can also occur, beginning as early as a few days after Sg.

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3
Q

What is the etiology of HO?

A

The etiology of HO is not completely understood. It is assumed that pluri potent mesenchymal cells present in periarticular ST and develop into osteoblastic stem cells, which then produce bone.

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4
Q

What are the highest risk factors for developing HO?

A

Pts who already have ipsi or contralat HO carry the greatest risk of developing further HO. Their risk is 80%–100%. Pts with osteophytes at the femoral head and socket, acetabular fractures, ankylosing spondylitis, and other hyperostosis conditions of the skeleton also carry a high risk for HO. This condition is more common in males than in females.

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