Back Pain profoma Flashcards

1
Q

What are the causes of back pain?

A

Malignancy

Infections:
- Disciitis
- Vertebral osteomyelitis

Mechanical back pain:
- Osteoarthritis of the spine
- Prolapsed intervertebral disc
- Vertebral crush fracture
- Spinal stenosis/spondylolisthesis

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2
Q

What are the Red-flag symptoms of back pain?

A

Bowel or bladder dysfunction- loss of anal sphincter tone or urinary retention

Constant, progressive pain unrelieved by rest

Major trauma

Unexplained weight loss & nigh sweats

Thoracic back pain

Immunosuppression

UTI

History of cancer

IV Drug use

Prolonged use of corticosteroids

Osteoporosis

Global or progressive motor weakness in lower limbs.

Duration of lower back pain is over 6 weeks & not improving w/ conservative management.

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3
Q

Initial investigation for back pain

A
  1. Nerve root irritation tests - i.e. straight leg raises, femoral stretch test…
  2. Blood tests - useful if you suspect infection, cancer, metabolic or inflammatory disorders.
  3. MRI - useful for most spinal conditions that you are trying to rule out.
    - Used to check nerves
  4. X-ray- useful for compression fractures but can be used in malignancy or spinal stenosis too.
  5. Bone scintigraphy (isotope bone scan) - can help diagnose cancer.
    - identifies areas of physical & chemical changes in bone.
  6. CT for positioning of the bones
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4
Q

Management for back pain

A
  1. Simple low back pain:
    - NSAIDs e.g. ibuprofen, naproxen
    - Encourage normal activities & return to work.
    - Loose weight & group exercise.
    - Educate - explain it’s self-limiting & exercise helps.
    - Safety net - “come back in 6 weeks if hasn’t improved”.
    - Do not refer for imaging unless it will change care.
  2. If the simple lower back pain isn’t getting better:
    - Massage or spinal manipulation.
    - Psychological therapy e.g. CBT
    - weak opioids.
    - Low dose anti-depressants may help sleep & mood.
    - Epidural or facet joint injection
  3. Red flag back pain:
    - Cauda equina or infection - urgently to A&E & take MRI!
    - Cancer - urgent MRI or x-ray & pain relief using WHO ladder.
    - Inflammatory back pain - refer to rheumatologist.
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5
Q

Epidemiology of mechanical back pain

A

80% of population

Patients over 60 yr rarely present w/ mechanical back pain
- symptoms usually subside
- due to stiffening of a mobile spine.

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6
Q

Aetiology and pathophysiology of mechanical back pain

A

features of osteoarthritis:
- joint space destruction
- osteophyte formation.

Degenerative disc disease occurs w/ ageing & is related to decreased water content in nucleus pulposus. - Disc space narrows & the segment becomes more mobile.
- This abnormal movement, together w/ inability to distribute load, causes pain

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7
Q

Clinical presentation of mechanical back pain? Investigations? Management?

A
  • Onset often sudden & precipitated by bending or lifting.
  • Pain worse in the evening & on movement.
  • Pain improves on rest.
  • Pain in lumbosacral, buttock and thigh regions.
  • Does not usually radiate to legs, if it does, then the pain doesn’t travel below the knee.
  • Muscle spasms
  • No systemic features
  • No clear-cut nerve root distribution.
  • Loss of lumbar lordosis

Investigation:
- x-ray may show- OA, minor disc narrowing or normal spine
- CRP, ESR, LFT etc all normal

Management:
- NSAID, rest, physio
- no surgery required

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8
Q

What is a prolapsed disc?

A

When part of the nucleus pulposus herniates through the annulus fibrosus (due to tear or rupture) & presses on spinal nerve root.

Also known as herniated disc

different to bulging- fluid bulging out slightly but not fully out

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9
Q

Aetiology and pathophysiology of prolapsed disc

A

herniation of disc material tends to occur posterolaterally where the annulus is thinner.

Central disc prolapse can occur & press on combined nerve roots, including those supplying bladder & bowel (cauda equina syndrome).

Prolapse can occur w/out spinal root involvement
- patient will have symptoms of back pain but not true sciatica.

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10
Q

Clinical presentation of prolapsed disc

A

Commonly occurs at L5-S1 or L4-L5

UNILATERAL sciatica
- Severe pain radiating down the leg as far as the toes.
- numbness + tingling + weakness of foot.

uncomfortable to sit or stand
- abnormal posture- stooping to affected side & standing w/ knee flexed to relieve pressure on dura
- Unable to stand on tip toes or heels due to weakness

Positive straight leg raise

Positive trendelengubrgs- L5 or L5 compressed

Loss of reflexes such as ankle jerk - common in L5 - S1 compression.

Cauda equina!- check for red flags!!!

Investigations
- take MRI - don’t take unless pain present for 4-6 weeks
- X-ray usually normal- don’t to exclude bony pathology e.g. spondylolisthesis
- Blood tests

Management
- NSAID, rest, physio
- Surgical diseconomy only required if cauda equina or pain more than 3 months
- Lumbar nerve root injection can provide diagnosis & treatment for nerve root compression.
- if pain > 3 months- surgery- will not treat but will improve leg symptoms

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11
Q

What is spondylolysis? What is spondylolithesis

A

Spondylolysis is a crack in the Pars Interarticularis (a small segment of bone that joins the facet joints in the spine).

Spondylolithesis is where the crack has allowed the whole vertebra to move forwards.

Related to sports injuries in teenagers

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12
Q

Clinical presentation of spondylolysis & spondylolithesis

A

Can be asymptomatic

low back pain.

Sciatica of spine possible if nerve root compressed

kyphosis possible

Radicular symptoms more common in adults

Central spinal tenderness.

Movement usually preserved, but classically hyperextension is painful.

Management
- X-ray to see if bones are out of place
- MRI if nerve root irritation is suspected.
-CT for lesions.

Conservative treatment - PT, NSAIDs, rest (short period) & corticosteroid injections.
- Spinal fusion in rare cases.

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13
Q

What is spinal stenosis?

A

A narrowing of spinal canal which can put pressure on your spinal cord e.g. by osteophytes, herniated discs, tumours, fractures.

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14
Q

Clinical presentation of spinal stenosis? Management?

A
  • Can be bilateral leg pain that is brought on by walking
  • Intermittent back pain, burning, heaviness, weakness or numbness radiating to thigh or calves
  • Pain worse on prolonged standing/exercise & better on sitting or lying down.
  • Better when leaning forwards so walking uphill is easier.
  • Fatigue on walking & activities
  • Typically seen in older patients
  • Risk fcators include previous back surgery & manual labour

Management:
- Get an MRI
- Temporary reduction in physical activity
- NSAIDs and Paracetamol
- Corticosteroids if pain isn’t being controlled after 7 days (but this is controversial).
- Spinal fusion can be used for serious cases.

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15
Q

What is scoliosis?

A

A lateral curved spine w/ uneven shoulders & leaning to 1 side

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16
Q

Management for scoliosis

A
  • X-rays show bones & MRI for other abnormalities.
  • Treatment is often bracing or sometimes surgery.
  • Analgesia if needed
17
Q

What is disciitis & vertebral osteomyelitis?

A
  • Infection of disc or vertebrae.
  • Haematogenous spread
  • Usually one pathogen - commonly staph. aureus
18
Q

Clinical presentation of disciitis & vertebral osteomyelitis? Investigation? Management?

A
  • Insidious onset of pain
  • spinal tenderness.
  • Abrupt onset of fever
  • Back stiffness, restricted motion, guarded walking,& spine tenderness.
  • Nerve root compression (15%)

Investigation:
- X-ray shows narrowed disc space & boney destruction.
- CT used for guided biopsy for cultures.
- MRI to detect abssesses.
- Isotope bone scan will be v. hot in affected area.
- Blood tests - CRP, ESR & WCC raised.

Management:
- IV antibiotics for 6 weeks
- MRI follow up 6 weeks later.
- Surgery - to drain abscess.

19
Q

What is spinal epidural abscess?

A

A rare suppurative (discharges pus) infection found in the epidural space.

Abscesses enclosed w/in bone of the spinal column can expand to compress the spinal cord.

20
Q

Presentation of spinal epidural abscess? Investigation? Management?

A
  • Focal spinal process pain
  • Fever!
  • Weakness of extremities - including motor weakness & sensory disturbances.
  • History of diabetes, IV drug use, HIV, immunosuppression, previous spinal surgery or trauma.
  • Endocarditis is commonest cause of Staph aureus abcess.

Investigation:
- Raised inflammatory markers are present & abscess needs to be aspirated & analysed.

Management
- IV antibiotics are needed w/ surgical decompression for those w/ neurological deficits.

21
Q

What is metastatic cancer? Symptoms? Investigations?

A

Where a tumour from another part of the body e.g. the breast, lung, prostate, thyroid or kidney has metastasised.

  • Night pain & pain at rest
  • Systemic symptoms e.g. fever, chills, weight loss and malaise.
  • Neurological deficits

X ray/MRI/CT and bone scan to investigate

22
Q

What is multiple myeloma?

A

A cancer characterised by proliferation of plasma cells (WBC) in the bone marrow

23
Q

Clinical presentation of multiple myeloma? Investigations? Management?

A
  • Severe bone pain - deep, aching pain that is poorly localised, severe at night & not improved by analgesia
  • Often present w/ fatigue due to anaemia.

Bone marrow biopsy, urine & serum electrophosesis, Bence-Jones proteins in urine used to investigate.

Management involves chemotherapy & stem cell transplant.

24
Q

What is vertebral compression fracture?

A

The collapse of a spinal vertebra due to compression of the bone causing a fracture.

25
Q

Clinical presentation of vertebral compression fractures? Investigation? Management?

A
  • Pain at rest & at night.
  • Patient usually has had previous compression fractures, has osteoporosis or has risk factors for osteoporosis.
  • increased kyphosis of spine.

Get an x-ray.

Management:
- analgesia using WHO pain ladder - review of their osteoporosis management.
- Surgery where cement is used to stabilise the bone (kyphoplasty).

26
Q

What is Sciatica?

A

Pain, numbness or tingling felt down the leg due to compression of sciatic nerve usually at L5 & S1.

  • Caused by a herniated disc, osteophytes, a tumour, spinal stenosis or damage by metabolic diseases e.g. diabetes.

RESTRICTED/PAINFUL LEG RAISE> SCIATICA

NSAID + rest + surgical decompression if necessary

27
Q

What is lumbar muscle strain/ sprain? Management?

A

An overstretch or tear to the muscles in the back = spasm.

  • Sharp intense pain for 1-2 days

No imaging abnormalities.

Most patients recover on their own w/in 3 months.

Usual activities, NSAIDs, PT, saftey net 6 weeks.

28
Q

Radiological examples of spine?

A

NOTE: look at notes for radiological imaging!!!!

https://www.notion.so/PBL-week-13-13e7f545d1e747c09b35b782ab1516ce

if in doubt, further imaging of back pain is always indicated in the form of CT or MRI
- MRI- disc or nerve roots
- CT- bony pathology

29
Q

How to know if its technical back pain or inflammatory?

A

back pain worse at rest & improves w/ exercise- sign of inflammatory conditions= so AS!