Back Conditions Flashcards

Subtopics: approach- back pain, approach: inflammatory conditions of the spine; approach: degenerative spine deformities

1
Q

SPINAL DEFORMITIES AND DEGENERATION

Spinal deformities occur in either the sagittal or coronal plane. Define both:

  • Coronal plane imbalance
  • Sagittal plane imbalance
A

Coronal plane imbalance
- Lateral deviation of the normal vertical line > 10 degrees

Sagittal plane imbalance
- Radiographic sagittal imbalance of > 5 cm

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2
Q

SPINAL DEFORMITIES AND DEGENERATION

T/F The patients who typically present with spinal deformities/ imbalances are patients in the 60s, more so in females

A

False
Male= female, 60s .

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3
Q

SPINAL DEFORMITIES AND DEGENERATION

Locate idiopathic scoliosis vs degenerative scoliosis

A

SPINAL DEFORMITIES AND DEGENERATION

Idiopathic scoliosis = thoracic spine

Degenerative scoliosis = lumbar spine

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4
Q

SPINAL DEFORMITIES AND DEGENERATION

  • Describe the pathoanatomy of degenerative scoliosis
  • List 4 conditions that may contribute to loss of sagittal plane balance.
A

Degenerative scoliosis results from the asymmetric degeneration in joint space and/or facet joints in the spine.

  1. OA
  2. Pre-existing scoliosis
  3. Iatrogenic instability
  4. Degenerative disk disease ( group of conditions in which disk material is displaced into the spinal canal&raquo_space; protrusion/ herniation/ sequestration)
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5
Q

SPINAL DEFORMITIES AND DEGENERATION

True or false: Worse prognosis in spinal instability is seen in the following patients:

  • Depleted ability to compensate (e.g. retroverted pelvis and obliterated lumbar lordosis)
  • Obliquity as L/S junction
  • Severely positive sagittal balance
A

True

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6
Q

SPINAL DEFORMITIES AND DEGENERATION

Progression of spinal deformities depend on the curve magnitude and additional risk factors. Elaborate on these.

A

Curve magnitude
- Curve < 30 degrees&raquo_space; rarely progresses
- Curve > 50 degrees&raquo_space; likely to progress.

Risk factors
- Pre-existing rotational changes
- Intercrestal line below L4-5

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7
Q

SPINAL DEFORMITIES AND DEGENERATION

List 5 types of spinal deformities

A
  1. Idiopathic (residual, d/t untreated adolescent idiopathic scoliosis)
  2. Degenerative (de novo, d/t degeneration)
  3. Post-traumatic
  4. Iatrogenic
  5. Paralysis
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8
Q

SPINAL DEFORMITIES AND DEGENERATION

List and explain the 3 main symptoms these patients present with.

A
  1. Low back pain (most common)
    - Caused by spondylosis OR micro/macro instability OR discogenic pain.
    - More severe than the general population.
  2. Neurogenic claudication
    - Pain in lower extremities and buttock not relieved by sitting/ forward flexion. Caused by spinal stenosis on the concave side of the curve.
  3. Radicular leg pain and weakness.
    - Caused by foraminal and lateral recess stenosis. Worse in concavity of the deformity where there is vertebral body rotation/ translation.
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9
Q

SPINAL DEFORMITIES AND DEGENERATION

List 3 main findings on physical exam

A
  1. Deformity
  2. Rigidity
  3. Radiculopathy on neurological exam
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10
Q

SPINAL DEFORMITIES AND DEGENERATION

List and account for imaging modalities needed in spinal instability.

A
  1. Whole spine AP + lat and bending x-ray
  2. CT scan
  3. CT myelogram
  4. MRI (if lower extremity pain and possible nerve compression )
  5. Dexa scan - to identify bone density for surgical planning
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11
Q

SPINAL DEFORMITIES AND DEGENERATION

Treatment: non-operative

  • What is the indication of non-operative Mx?
  • List and elaborate on the 4 non-operative modalities of managing spinal deformities.
A
  • Indicated in coronal curves of < 30 degrees (less likely to progress)

Management:
1. Oral medications - NSAIDS, Amitriptylline
2. Physiotherapy- core strengthening
3. Corticosteroid injections and nerve root blocks - therapeutic and diagnostic
4. Bracing - slows down progression, and increases comfort.

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12
Q

SPINAL DEFORMITIES AND DEGENERATION

Surgical correction has a very high complication rate and includes surgical curve correction with instrumented fusion. List 5 indications for surgery

A
  1. Coronal curves > 50 degrees
  2. Sagittal imbalance
  3. Curve progression
  4. Intractable pain or radicular pain that failed nonoperative Mx
  5. Cardiopulmonary decline
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13
Q

SPINAL DEFORMITIES AND DEGENERATION

The goals of surgery are to restore spinal balance. Sagittal plane balance is the most reliable predictor of clinical symptoms post-op. Surgery aims to relieve pain and obtain fusion.

List 6 complications of spinal surgery in these patients.

A
  1. Thromboembolism
  2. Pseudoarthrosis (most common)
    3.Infection - UTI commonest
  3. Neurologic compromise
    Pulmonary embolism
  4. Instrumentation problems e.g. loosening or breakage
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14
Q

SPINAL DEFORMITIES AND DEGENERATION

  • What is pseudo-arthrosis
  • List 4 risk factors
A
  • Def: A condition where a fracture fails to heal and forms a fibrous joint instead (pseudo-arthrosis)
  1. Age > 55
  2. Smoker
  3. Kyphosis and positive sagittal balance > 5cm
  4. Hip arthritis
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15
Q

OSSIFICATION POSTERIOR LONGITUDINAL LIGAMENT

  • This is a cause of cervical myelopathy in which patients?
  • The cause is not clear but there are some associated risk factors, list 5.
A
  • Common in Asians (2-3% of the Japanese population), mostly in men in their 50s-60s.

Risk factors:
- Diabetes
- High salt, low meat, low calcium content in diet.
- Obesity.
- Mechanical stress

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16
Q

OSSIFICATION POSTERIOR LONGITUDINAL LIGAMENT

  • These patients are often asymptomatic but may have signs or symptoms of myelopathy (as a result of spinal cord compression). List 5 signs.
  • What 3 imaging can be used to make the diagnosis?
A

Cervical myelopathy signs:
1. Unsteady gait
2. Clumsy
3. + Babinski
4. Sustained clonus
6. + Hoffmann sign
7. Brisk reflexes.

Imaging: X-ray: shows ossification of posterior ligament.
CT: look at bony anatomy
MRI: evaluate spinal cord

17
Q

OSSIFICATION POSTERIOR LONGITUDINAL LIGAMENT

  • What are the complications of OPLL?
  • Describe the treatment of OPLL
A

Complications:
1. Recurrence post-surgery
2. Permanent SCI

Treatment:
- Mild sx/sx: observe
- Surgery to decompress the spinal cord and stabilize the spine

18
Q

RHEUMATOID CERVICAL SPONDYLITIS

Fill in the blanks

RA is an auto-immune disease that affects the (1) ______ joints in 1-3% of the population.
The duration is (2)_____, the pattern is (3)______ and although it commonly affects small joints, it can also affect large joints.
If mostly affects (4)______ (gender) at the ages of (5) _______.

Describe the typical RA X-ray, serology and histology

A
  1. synovial
  2. chronic
  3. symmetric polyarthritis affecting PIPs, MCPs, wrist
  4. females
  5. 40-50 yo

Xray: erosions (marginal)
Serology: positive RF
Histology: proliferative synovitis, fibrinoid necrosis surrounded by a palisade of inflammatory cells.

19
Q

RHEUMATOID CERVICAL SPONDYLITIS

Pannus formation leads to the destruction of the ligaments and bone leading to instability.

  • List the RA manifestations (3 radiological entities), therefore, in the cervical vertebrae
  • Describe the Xray findings and 2 other imaging that can be done (& why).
A
  1. Atlantoaxial subluxation (unstable c1/c2)
  2. Basilar invagination (superior migration of odontoid above the foramen magnum)
  3. Subaxial subluxation

On XRAY:
- Flexion-extension views: ADI > 3.5 mm
- Lateral Xray to assess the basillar invagination and subaxial subluxation > 4mm

Other imaging: CT for bony anatomy and MRI for spinal cord compression

20
Q

RHEUMATOID CERVICAL SPONDYLITIS

  • Describe the symptoms that the pt with RA of the cervical spine will present with (3)
  • What complications can we expect with cervical RA?
  • Describe the treatment of cervical RA.
A

Symptoms:
1. Cervical myelopathy
2. Neck pain and stiffness
3. Occipital headaches

Complications:
1. Progression of neurology with sudden paralysis
2. Pseudoarthrosis secondary to fibrosis
3. Failure to improve symptoms

Treatment:
1. Rx the RA
2. Surgical spinal decompression and stabilization e.g. C1/2 fusion/ occiput/c2 fusion

21
Q

ANKYLOSING SPONDYLITIS

Describe the:

  • Pathogenesis:
  • Serology & genetics:
    -Joints targeted:
  • Typical patient
A
  • Pathogenesis&raquo_space; autoimmune
  • Serology & genetics&raquo_space; seronegative, HLA-B27 +ve
    -Joints targeted: SI joints, spinal joints, symphysis pubis
  • Typical patient: men, 3rd decade of life
22
Q

ANKYLOSING SPONDYLITIS

  1. What is the diagnostic criteria of AnkSpond? (3)
  2. List 3 Orthopaedic manifestations of Ank Spond (4)
A
  1. DX CRITERIA:
    - Bilateral sacroiliitis
    - Uveitis
    - HLA-B27 +ve
  2. ORTHOPAEDIC MANIFESTATIONS
    - BIlateral SI joint inflammation
    - Progressive kyphotic deformity
    - Cervical spine fractures
    - Large joint arthritis
23
Q

ANKLYLOSING SPONDYLITIS

  • Describe how the patient presents to you (symptoms and signs)
  • You are now examining this patient. What will you find?
  • You highly suspect Ank Spond. What investigations will you do? (Labs, Imaging)
A

Symptoms: (1) The pt will complain of lumbosacral pain and stiffness that is worse in the mornings. They may or may not have thoracic/ cervical pain later in life. (2) They may have loss of horizontal gaze and (3) Shortness of breath from the kyphosis.

Signs: (1) Limited chest wall expansion (2) Decreased spine motion (3) Kyphotic spine motion (chin-on-chest deformity). Other joints may also be stiff.

Investigations: Labs: HLA-B27 and ESR
Imaging: Standing full AP and lateral x-ray (marginal syndesmophytes, anterior and posterior longitudinal ligaments ossification, SI joint sclerosis/ fuzziness. Later&raquo_space; bamboo spine)
CT if suspect fractures of the spine. MRI&raquo_space; detects inflammation in early disease and sees epidural hemorrhage in spinal fractures. Bone scan» shows inflammation of the SI joint.

24
Q

ANKYLOSING SPONDYLITIS

  1. List 3 of complications of Ank Spon
  2. Broadly describe the management of ank spond
A
  1. Fractures, degeneration (OA), Stiff spine
  2. Non-op: NSAIDS, cox-2 inhibitors, physiotherapy, biologicals, surgery (Mx of fractures, joint fusion/ osteotomies to decrease kyphosis)
25
Q

DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS (DISH )

  • This is a very common cause of back pain and spinal stiffness, more in men > 50 yo. Describe the typical pathology
  • It is more common in the thoracic > cervical> lumbar spine. List 3 commonly associated risk factors
A
  • Pathology: non-marginal syndesmophytes at least 3 successive levels.
  • Gout, Hyperlipidaemia, Diabetes
26
Q

DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS (DISH)

  • Patients are often asymptomatic. Symptoms will be determined by where the lesion is. Explain.
  • Describe findings on Xray, bone scan.
  • Why would you do an MRI/CT?
A

SYMPTOMS
- Pts are often asymptomatic. May complain of mild back pain or stiffness. If in the cervix: pain and stiffness, stridor, hoarseness and sleep apnoea.
- Decreased ROM&raquo_space; may have a myelopathy

ON XRAY:
- non-marginal syndesmophytes, preservation of joint space.

BONE SCAN
- Increased uptake

CT/MRI&raquo_space; if pt had trauma and you suspect a fracture.

27
Q

DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS (DISH )

  • Describe the treatment of DISH
  • T/F: Complications of DISH include heterotopic ossification after hip surgery and mortality after trauma.
A
  • TREATMENT:
    Medical» NSAIDS, Biphosphonates
    Non-medical» Braces, physio, activity modification, spinal decompression and stabilisation if myelopathy.