B3.2 - The Endocrine System Flashcards
What are hormones? Where are they made, and how are they transported?
- They are chemical messengers
- Made in the endocrine glands and secreted into the plasma in the blood to be transported to the target organ to cause a response.
What is homeostasis?
Maintenance of a constant internal environment.
Examples of major endocrine glands and hormones they produce?
- Hypothalamus and pituitary gland: produce hormones that regulate the production of other hormones
- Thyroid gland: produce thyroxine
- Adrenal glands: produce adrenaline
- Pancreas: produce insulin
- Ovaries: oestrogen and progesterone
- Testes: testosterone
What are target cells?
- Hormones travel all over the body but only target organs respond.
- Hormones diffuse in the blood and bind to specific receptors for that hormone on the membrane or cytoplasm of cells, those are the target cells.
- This stimulates the target cells to respond.
What is thyroxine and its function?
Thyroxine is produced in the thyroid gland and regulates your body’s metabolic rate - speed that your body transfers energy from its chemical stores in order to perform functions.
What is negative feedback?
A system that detects a change in a condition, the system acts to return the conditions to a desired level.
Explain how thyroxine levels are controlled.
Hypothalamus detects cell needs more energy > pituitary releases TSH > thyroid secretes thyroxine > hypothalamus detects cells have enough energy > inhibits TSH via the pituitary > thyroid stops producing thyroxine.
What is adrenaline?
A hormone that is secreted in times of stress (via the adrenal glands).
Prepares the body for intensive action.
How does the body respond when you are threatened or scared?
- Heart rate and blood pressure increases as adrenaline binds to receptors in the heart stimulating this action of contracting more forcefully.
- Results in quicker respiration, producing more ATP.
- Binds to liver to help breakdown glucose in glycogen stores.
What are the 4 hormones that control the menstrual cycle and their roles?
All made in the ovaries
LH - Luteinising hormone - stimulates the release of an egg (ovulation)
FSH - follicle stimulating hormone - stimulates the maturing of an egg. (Stimulates ovaries to produce oestrogen)
Oestrogen - builds up the lining of the uterus wall. (Stimulates LH and inhibits FSH so only one egg is released per cycle)
Progesterone - maintains the lining of the uterus wall in case of receiving a fertilised egg. (Levels are high during pregnancy)
Stage 1 of the menstrual cycle
- Day 1-4 - uterus lining breaks down and is released (menstruation).
Stage 2 of the menstrual cycle
- Day 4-14, lining of the uterus builds up (oestrogen) again ready to receive a fertilised egg. (egg is maturing (FSH))
Stage 3 of the menstrual cycle
- Egg is released after maturing from an ovary at about Day 14 (LH)
Stage 4 of the menstrual cycle
- Day 14-28 the uterus lining is maintained in case a fertilised egg arrives, if one doesn’t, the lining will breakdown and the cycle starts again. (Progesterone)
Two classifications of contraception.
Hormonal - use hormones to disrupt females reproductive cycle.
Non-hormonal - physical barriers protecting the sperm from reaching the egg or spermicides to kill sperm.