B3.1 and B3.3 (Test 1- Monday 26th April) Flashcards

1
Q

What are the 2 parts of the Nervous System and their functions?

A

-Central Nervous System (CNS)- controls most functions in the body and mind (brain and spinal cord).

-Peripheral Nervous System (PNS)- this includes nerves leading to & from the brain and spinal cord.
Primary role of the PNS is to connect the CNS to the organs, limbs, and skin.

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2
Q

What are neurones?

A

Neurones are a particular type of cell (nerve cell) that carry information messages or signals to and from the brain and the rest of the body.
Groups of neurones are called nerves.
They are specialised for transmitting messages in the form of an electrical impulse.

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3
Q

Why do neurones have an extended shape?

A

Neurones have an extended shape so that they can carry nerve impulses from one part of the body to another.
It’s designed that way by the neurone to slow down the action potential of signals in order to optimise the refraction ratio.

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4
Q

Describe a motor neurone:

A

A motor neurone is a type of nerve cell whose cell body is located in the motor cortex, brainstem or the spinal cord
-And whose axon projects to the spinal cord or outside of the spinal cord to directly or indirectly control effector organs, mainly muscles (contract) and glands (secrete).

A motor neurone contains:
-dendrites, nucleus, cell body, myelin sheath, axon, motor end plate.

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5
Q

Describe a sensory neurone:

A
  • Sensory neurones are nerve cells within the nervous system responsible for converting external stimuli from the organism’s environment into internal electrical impulses.
  • For example, some sensory neurones respond to tactile stimuli and can activate motor neurones in order to achieve muscle contraction.

Sensory neurones contain:
-pressure receptor, myelin sheath, axon, cell body, dendrites.

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6
Q

Describe a relay neurone:

A
  • Relay neurones are found between sensory input and motor output/response.
  • Relay neurones are found in the brain and spinal cord (CNS) and allow sensory and motor neurones to communicate.

Relay neurone contains:
-dendrites, cell body, axon, synaptic endings.

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7
Q

What is the function of the axon?

A

The axon allows neurones to transmit electrical and chemical signals to other cells.
-It is where the electrical impulse travels down.

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8
Q

What is the function of the myelin sheath?

A

-The myelin sheath is a white, fatty substance (protein and fatty substances) that prevents leakage of electrical impulses through insulation.

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9
Q

What is the function of dendrites?

A
  • The dendrites connect to other neurones to make a new nerve pathway.
  • They contain lots of mitochondria- create lots of ATP.
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10
Q

What is the function of the motor end plate?

A

The motor end plate connect to muscles (contract) or glands (secrete).

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11
Q

Describe the nerve pathway:

A
(Top to bottom- nerve pathway):
Stimulus         (change in environment)
      |
Receptor  (5 senses)
      |
(Sensory neurone)
      |
(relay neurone)
      |
CNS     (brain/spinal cord- co-ordinate response)
      |
(motor neurone)
      |
Effector  (muscle or gland)
      |
Response.
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12
Q

What is a reflex action?

A

-A reflex action is an automatic, fast, involuntary reaction
-You do NOT have any control over these actions.
-They are survival responses.
-They can bypass the brain
-They take the shortest route- from receptor->effector.
=Reflex Arc.

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13
Q

Name some reflex actions:

A
  • pupil constriction
  • knee jerk
  • startle reflex (babies)
  • stepping reflex (babies)
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14
Q

Explain the pathway taken by a reflex arc (example of a reflex action):

A

1) A stimulus is a change in the environment of an organism.
2) This is detected by a receptor, such as the eye.
2) Impulses from a receptor pass along a sensory neurone to the CNS (the co-ordinator)
3) A chemical crosses the gap (synapse) between a sensory neurone and a relay neurone.
4) Then a chemical crosses the synapse between a relay neurone and a motor neurone.
5) The motor neurone carries an impulse to an effector which can be a muscle or a gland.
6) The muscle responds by contracting and a gland responds by releasing chemical substances.

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15
Q

What is a synapse?

A
  • A synapse is where 2 or more neurones meet,
  • There is a small gap around 2-3 micrometres big
  • Signals cross the gap using chemical released by a neurone.
  • This chemical is called a neurotransmitter (NT) (electrolyte charged) (this can be sodium ions, but there are many different types of NT that diffuse across the synapse.)
  • The gap between the two neurones can also be called the synaptic cleft.
  • The electric signal that travels through the axon in the neurone comes in contact with the end of the neurone and the signal is temporarily converted into chemical energy (chemical transmitter molecules).
  • These chemical transmitter molecules diffuse across the synaptic cleft.
  • Then, the chemical transmitted molecules bind to receptors on the other neurone, which opens the channels, allowing the chemical energy to be re-converted into electrical energy/signal.
  • The nerve impulse is then initiated in the next neurone
  • This repeats until the effector is reached.
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16
Q

What is the function of the brain?

A
  • The brain coordinates responses to changes in the internal conditions and the environment.
  • The brain and spinal cord form the CNS which process information that comes from body via neurones.
  • CNS receives electrical signals from neurones that are stimulated by change in both internal and external environment.
  • It sends out electrical signals along other neurones to bring about a suitable response.
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17
Q

What is the function of the cerebrum:

A

This is the largest part of the brain

It is responsible for things like consciousness, intelligence, memory and language.

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18
Q

What is the function of the Hypothalamus?

A

-The hypothalamus is involved in maintaining body temperature at the normal level.
It also produces hormones that control the pituitary gland.

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19
Q

What is the function of the pituitary gland?

A

The pituitary gland produces many important hormones, such as those involved in the menstrual cycle.

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20
Q

What is the function of the medulla?

A

The medulla controls unconscious activities like breathing and heart rate.

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21
Q

What is the function of the cerebellum?

A

The cerebellum is responsible for muscle coordination.

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22
Q

Describe a non-intrusive technique to investigate the brain’s function?

A
  • Neuroscientists can use electrodes to stimulate different parts of the brain.
  • By observing the resulting behaviour, it is possible to work out the function of the region stimulated.
  • Observations that may be recorded include a change in emotion, sudden movement or an increase in heart rate,
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23
Q

Describe the uses of an MRI scan:

A
  • MRI scan uses strong magnets and radio waves to produce detailed images of the inside of the brain/body.
  • Most common use is: anatomical structure.
  • Used to identify presence of tumours or haemorrhages.
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24
Q

Describe the uses of a PET scan:

A

PET scanning produces detailed 3D images that can be used to investigate brain’s activity.
A substance that emits radiation is injected into the patients bloodstream.
In the scanner, radiation can be detected as it collects in different parts of the body, including the brain.
-During PET scan, patient is asked to perform tasks.
-Depending on tasks, different images are produced.

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25
Q

Describe the uses of CT scan:

A

-A CT scan uses x-rays + special computer technology to produce images of ‘slices’ showing inside the body.
Bone absorbs x-rays well; soft tissues don’t.
Different tissues absorb different level of x-ray, so you get different shades (greyscale).
ONLY shows brain’s anatomical structure.

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26
Q

Describe some difficulties of investigating the brain’s function:

A
  • If a person is severely brain damaged, it may be unethical to study them as they might not be able to give informed consent.
  • Studying the brains of people who have died relies on people donating their brains for research- not many people are willing to do this.
  • There can be difficulty reaching some areas of the brain during operations.
  • Difficulty in obtaining volunteers.
  • Operations may cause irreversible damage- nerve tissue cannot heal and nerve cells cannot be re-made.
  • Placebo effect.
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27
Q

Describe an experiment designed to look at reaction times (name all types of variables:)

A

Ruler-dropping experiment.

  • Independent variable: Right hand vs Left hand
  • Dependent variable: distance between 0 and catching on ruler.
  • Controlled variable: same catcher, start drop from ocm, same fingers at 3cm, random dropping, same ruler (same width, same mass), large sample size (10x), number used is from top of the thumb every time.
28
Q

What is the formula for calculating reaction time?

A

time (s)= √2 x distance (m) ÷ acceleration as a result of gravity

acceleration= 9.81 m/s^2

29
Q

Name all the parts of the eye (look up on google a blank image and name the parts):

A

Parts of the eye:

  • pupil
  • cornea
  • suspensory ligaments
  • aqueous humour
  • iris
  • lens
  • conjunctiva
  • ciliary muscle/body
  • blind spot
  • optic nerve
  • vitreous humour
  • retina
  • choroid
  • sclera
30
Q

What is the function of the sclera:

A

-The sclera is the tough outer layer of the eye

31
Q

What is the function of the lens?

A

The lens focusses light rays on the retina.

32
Q

What is the function of the cornea?

A

The cornea is a transparent region of the sclera at the front of the eye,

33
Q

What is the function of the retina?

A

The retina is made up of light sensitive receptor cells that detect light.

34
Q

What is the function of the optic nerve?

A

The optic nerve carries impulses from the retina to the brain.

35
Q

What is the function of the cillary body?

A

The cillary body secretes the fluid that supports the front part of the eye (vitreous humour). It also contains the cillary muscle.

36
Q

What is the function of the suspensory ligaments?

A

The suspensory ligaments change the shape of the lens to focus light rays on the retina.

37
Q

What is the function of the iris?

A

The iris has sets of muscles that control the size of the pupil and regulate the light reaching the retina.

38
Q

What is the function of the pupil?

A

The pupil is the hole in the centre of the iris that allows light to pass through.

39
Q

Describe the route a light ray takes into the eye:

A

Route of light ray:

conjunctiva-cornea-vitreous humour-pupil-lens-aqueous humour-retina.

40
Q

How do our eyes see close and distant objects?

A
  • When objects are near, the lens needs to be short and fat. The ciliary muscles contract which relax the suspensory ligaments. The more rounded lens enables light to focus correctly on the retina.
  • When objects are far, the lens needs to be long and thin. The ciliary muscles relax which tauter the suspensory ligaments. The less rounded lens enables light to focus correctly on the retina.
41
Q

How do we focus light on the retina?

A

We focus light by..:

  • light enters the eye and is refracted twice (1x by cornea, 1x by lens)
  • light rays are focussed by lens
  • focal points at the back of the ye on the retina
  • image is inverted
  • brain corrects the image and turns it the correct way up.
  • muscles- contract, relax
  • ligaments- taut, slack.
42
Q

What is short-sightedness?

A
  • In short-sighted people, light focuses short of the retina.
  • It is corrected by using a divergent biconcave lens so light focuses correctly on the retina.
  • short-sighted people cannot focus on distant object well.
43
Q

What is long-sightedness?

A
  • in long-sighted people, light focuses long of the retina.
  • It is corrected using a biconvex lens so light focuses on the retina.
  • Long sighted people cannot focus on close objects very well.
44
Q

What happens to our eyes in bright light?

A
  • If too much light enters the eye, it can cause damage in the retina- often called “bleaching”
  • Pupil constricts- the size of pupil is controlled by 2 muscles: radial muscle and circular muscle.
  • These iris muscles are antagonistic.
  • radial muscle relaxes in bright light
  • circular muscle contracts in bright light.
45
Q

What happens to our eyes in dim light?

A
  • In the dark you need as many light rays entering the ye as possible to form an image.
  • pupil dilates- the size of pupil is controlled by 2 muscles: radial muscle and circular muscle.
  • These iris muscles are antagonistic.
  • radial muscle contracts in dim light
  • circular muscle relaxes in dim light.
46
Q

What is the function of rod cells:

A

Rod cells function as specialised neurones that convert visual stimuli in the form of photons (particles of light) into chemical and electrical stimuli that can be processed by the central nervous system.

  • Photo-receptive cells
  • 100x more sensitive to light than cones
  • form an image in low light intensity.
47
Q

What is the function of cone cells?

A

Cone cells are a type of photoreceptor cells that are in the retina of the eye which are responsible for colour vision as well as eye colour sensitivity; they function best in relatively bright light.

  • they detect colours
  • 3 types: red, green. blue (RGB)
  • can’t detect colour in low light intensities.
48
Q

What is the difference between the nervous system and the endocrine system?

A

Nervous system:

  • relies on neurones
  • electrical impluses
  • very fast
  • specific- 1 muscle pair, 1 gland etc.

Endocrine System:

  • secreted in blood by endocrine system
  • chemical proteins (except some sex hormones because they are steroid)
  • slow and long lasting (except for adrenaline)
  • general: can affect many organs at the same time.
49
Q

What is homeostasis?

A

-Homeostasis is the regulation of internal conditions to maintain a ‘steady state’.

50
Q

What is thermoregulation?

A

Thermoregulation is the control of body temperature.
The temperature change is controlled and detected by the hypothalamus.
Normal body temp in humans is 37ºC.
When the hypothalamus detects a change, it causes a response in the dermis.

51
Q

How does our skin keep us warm in cold places?

A
  • Hairs trap heat
  • Insulation- hairs stand on end to trap an insulating layer of air, which helps keep you warm.
  • Hairs are erect
  • Shivering- generates heat by respiring muscles which transfers energy to warm the body.
  • vasoconstriction- less heat lost by radiation.
  • no sweating.
  • erector muscles contract
  • Blood vessels near the surface of the skin constrict- vasoconstriction. It means less blood flows near the surface so less energy is transferred to the environment.
52
Q

How does our skin keep is cool in warm places?

A
  • heat is lost from the skin
  • Hairs lie flat (no insulation layer no heat trapped)
  • No shivering
  • erector muscles lie flat
  • sweat is produced. When the sweat evaporates, it transfers energy from your skin to the environment, cooling you down. This is called the latent heat effect.
  • blood vessels close to the surface of the skin dilate- this is called vasodilation. It allows more blood to flow near the surface so it can transfer more energy into the surroundings, which cools you down.
53
Q

What is the optimum BGL in our blood?

A

4-7 mmol/L

54
Q

What organ is the most sensitive to changes in the BGL?

A

The brain is very sensitive to changes in BGL and is often the first organ to be effected.

55
Q

What organ has cells that detect change in BGL?

A

The pancreas contains specialised cells that can detect change in the BGL.
The Pancreas will then respond by releasing 1 of 2 hormones, depending on the BGL.

56
Q

What is the target organ for the two hormones responsible for maintaining 4-7mmol/L BGL?

A

The target organ for these 2 hormones is the liver.

57
Q

What happens if the BGL is too low in the blood?

A
  • Pancreas will detect and respond by releasing Glucagon.
  • Glucagon travels in the bloodstream to the target organ- the liver.
  • In the liver, glucagon instructs cells to breakdown insoluble Glycogen (stored glucose) into glucose, and release it into the bloodstream.
  • the blood glucose concn returns to normal.
58
Q

What happens if the BGL is too high in the blood?

A
  • Pancreas will detect and respond by releasing Insulin.
  • Insulin travels in the bloodstream to the target organ- the liver.
  • In the liver, excess glucose is converted (as instructed by Insulin) into insoluble Glycogen, to be stored.
  • the blood glucose concn returns to normal.
59
Q

What is negative feedback?

A

-Negative Feedback is a regulatory response to changes in the body which decreases levels that are too high and increases levels that are too low.

60
Q

What is type 1 Diabetes?

A

Type 1 diabetes is a condition where the body is no longer able to produce sufficient insulin to control its blood glucose concentration. BGL rise and drop rapidly and multiple times a day.
it is caused by:
-genetic factors (inherited)

Cells in the pancreas that make insulin are destroyed (by patients immune system).

61
Q

What are the symptoms of Type 1 Diabetes?

A

Symptoms include:

  • fatigue
  • very thirsty
  • excessive urination
  • faint
62
Q

What is the treatment for Diabetes Type 1?

A
  • Insulin Injection
  • Insulin pump
  • Islet Cell transplantation
  • Pancreas transplant.
  • research with stem cell therapy.
63
Q

What is the word that describes too much glucose?

A

Hyperglycemia

64
Q

What is the word that describes too low glucose?

A

Hypoglycemia.

65
Q

What is Type 2 Diabetes?

A

Type 2 Diabetes is where a person becomes resistant to insulin (body cells don’t respond properly to the hormone).
This can also cause BGL to rise to a dangerous level.
Being overweight can increase your chance of developing this disease.
Type 2 Diabetes can be controlled by eating a healthy diet, exercising regularly and losing weight if necessary.
There are also some drugs available which improve the way the body cells responds to insulin.

66
Q

What is lysis?

A

Lysis is the breaking down of the membrane of a cell, often by viral, enzymic, or osmotic mechanisms that compromise its integrity.