B3.006 Prework 2 Influenza Vaccine Development and Effectiveness

Question 1

characterize the seasonal influenza vaccine

Answer 1

developed annually
effective 2 weeks after vaccination
injectable
inactivated virus or recombinant technology

Question 2

components of trivalent vaccine

Answer 2

influenza A H1N1
influenza A H3N2
influenza B

Question 3

components of quadrivalent vaccine

Answer 3

influenza A H1N1
influence A H3N2
2 different influenza B viruses

Question 4

describe the process of flu vaccine production

Answer 4

global influenza surveillance in >100 countries
2 vaccines developed annually (northern and southern hemispheres)
160 million US doses developed per year
begins 6-9 months before distribution
most common = egg based process (also mammalian cells and insect cell processes)

Question 5

flu vaccine recommendations

Answer 5

everyone >6 months
ideally by end of October (season peaks in January or later)
>65 high dose vaccine
6 mo-8 years need 2 doses if first vaccine

Question 6

can you get the flu from the flu vaccine?

Answer 6

NO
other viruses can cause flu like illness
-rhinovirus (common cold)
-respiratory syncytial virus

Question 7

benefits of the flu vaccine

Answer 7

flu prevention
milder illness
herd immunity

Question 8

flu vaccine effectiveness

Answer 8

works best in healthy adults and kids >2

50-60% effectiveness if matches well

Question 9

how do you calculate vaccine effectiveness

Answer 9

(1-odds ratio) *100
odds of vaccination among people with flu who saw a healthcare provider/ odds of vaccine among people without flu who saw healthcare provider

Question 10

what are ways other than vaccination to help prevent flu

Answer 10

wash hands
cover cough
stay home when sick