B2 - Organisation Flashcards
Where is lipase produced in the body (2 areas)?
- Small intestine
- Pancreas
Where is protease produced in the body (2 areas)?
- Stomach
- Pancreas
- Small intestine
Where is amylase produced in the body (3 areas)?
- Small intestine
- Mouth
- Pancreas
What is the role of bile?
- Emulsifies lipids
- Neutralises stomach acid
What chemical is used for a test to find protein?
Biuret reagent
What chemical is used for a test to find stach?
Iodine
What chemical is used for a test to find sugar?
Benedict’s solution
What chemical is used for a test to find lipids?
Sudan III / ethanol
What food uses biuret reagent to find it?
Protein
What food uses iodine to find it?
Starch
What food uses Benedict’s solution to find it?
Sugar
What food uses sudan III or ethanol to find it?
Lipids
What colour does biuret reagent turn when mixed with protein?
Pink / purple
What colour does iodine turn when mixed with starch?
Black / blue
What colour does Benedict’s solution turn when mixed with sugar?
Orange / red
What colour does sudan III / ethanol turn when mixed with lipids?
Red layer / cloudy
What is the role of the mouth?
Chew food into small pieces
What is the role of the stomach?
Churn / break down food
What is the role of the small intestine?
Absorb nutrients
What is the role of the large intestine?
Absorb water
What is the main function of the heart?
It’s responsible for pumping oxygenated and deoxygenated blood to different areas of the body
Which side of the heart sends deoxygenated blood to the lungs?
The right side
Which side of the heart sends oxygenated blood to the body?
The left side
What route does deoxygenated blood take through the heart?
Vena cava > right atrium > right ventricle > pulmonary artery > lungs
What route does oxygenated blood take through the heart?
Pulmonary vein > left atrium > left ventricle > aorta > body
Where is our natural pacemaker?
In the right atrium
What can be used to regulate an irregular heartbeat?
Artificial pacemaker
Our double circulatory system is made up of two circuits. What are they called?
- Pulmonary circuit (between the heart and lungs) - Systemic circuit (between the heart and the other organs)
What do red blood cells do?
Carry oxygen
What do white blood cells do?
Fight infection
What does plasma do?
Carry waste
What do platelets do?
Clot blood
What does CVD stand for?
Cardiovascular disease
What does CHD stand for?
Coronary heart disease
What are some treatments for CHD?
- Statins
- Stents
- Replacement heart valves
- Artificial blood
- Heart transplant
What do statins do?
They are drugs to lower your cholesterol levels
How do stents work?
Catheter inserted, with stent inside, into coronary artery > balloon inflated > catheter removed
What is a replacement valve?
A metal or animal valve to replace a faulty valve
What is a heart transplant?
Transplanting / replacing your heart (needed in case of heart failure)
What happens in CHD?
- Fatty deposits build up in the arteries - Narrows the lumen - Reduces blood flow - Heart gets a lack of oxygen
What is a tissue?
A group of similar cells that work together to perform a specific function
What is the function of muscle tissue?
To contract to move what it’s attached to
What is the function of glandular tissue?
It makes and secretes chemicals like enzymes or hormones
Where is epithelial tissue found?
It covers some parts of the body, e.g. the inside of the gut
What is the role of muscular tissue in the stomach?
Moves the stomach wall to churn up food.
What is the role of epithelial tissue in the stomach?
Covers the inside and outside of the stomach.
Explain what is meant by the term “organ system”.
A group of organs working together to perform a specific function.
What does the digestive system do?
Breaks down and absorbs food.
What is the role of glands in the digestive system? Give 2 examples.
They produce digestive juices.
What is the role of the liver in the digestive system?
Produces bile
What is the role of the stomach and small intestine in the digestive system?
- They both digest food
- Small intestine absorbs soluble food molecules
What is the role of the large intestine in the digestive system?
Absorbs water from undigested food (leaving faeces)
What are enzymes?
They are large proteins which break down large molecules into smaller, soluble ones
What are enzymes made out of?
Proteins are made of chains of amino acids.
These are folded into unique shapes (i.e. active sites).
Why can enzymes be described as biological catalysts?
- The body needs to speed up chemical reactions
- Raising body temperature isn’t a good way of doing this, because this accelerates unwanted reactions and harms cells
- So we have enzymes which speed up reactions instead
What is a catalyst?
A substance which increases the speed of a reaction without being altered or used up in the reaction.
The substance that an enzyme acts on is called the ______
Substrate
Why do enzymes usually only catalyse one reaction?
For enzymes to work, the substrate has to fit into its active site. If it doesn’t, the reaction won’t be catalysed
Why is the lock and key model of enzymes slightly inaccurate?
- The model shows the enzyme remaining the same after a reaction.
- The active site actually changes shape a little as the substrate binds to it (to fit tighter).
- This is referred to as the induced fit model.
Enzymes have an optimum ___ and ___, which is often ___
1) Temperature
2) pH
3) Neutral
What is meant by an enzyme being “denatured”? Describe how this happens and what leads up to it.
- An increase in temperature will increase the rate of reaction until the enzyme reaches its optimum temperature.
- At a certain temperature, bonds in an enzyme are broken.
- This changes the shape of the active site- substrate doesn’t fit.
The enzyme amylase catalyses the breakdown of starch to maltose. Iodine can be used to detect starch- if starch is present, iodine solution will change from browny-orange to blue-black.
Describe how you could investigate the effect of pH on the rate of amylase activity.
1) Put a drop of iodine solution into every well of a spotting tile.
2) Place a bunsen burner on a heatproof mat and a tripod and gauze over the bunsen burner.
3) Put a beaker of water on top of the gauze and heat it until it reacher 35°C (measure using a thermometer). Try to keep the water temperature constant throughout the experiment.
4) Put a boiling tube in the beaker. Use a syringe to add 1cm3 of amylase solution and 1cm3 of a buffer solution (pH 5) to the boiling tube.
5) Use a different syringe to add 5cm3 of a starch solution to the boiling tube. Immediately mix the contents and start a stopwatch.
6) Use continuous sampling to record how long it takes for the amylase to break down all of the starch. Do this by using a pipette to take a sample from the boiling tube every 30 seconds and putting a drop into different wells of the spotting tile. When the iodine solution remains browny-orange, starch is no longer present.
7) Repeat the experiment with buffer solutions of different pH values to see how pH affects the time taken for the starch to be broken down.
The enzymes used in digestion are produced by ___ and then released into the ___ to mix with food.
1) Specialised cells in glands and in the gut lining
2) Gut
What do enzymes do to starch, proteins and fats, and why?
They are molecules too big to pass through the walls of the digestive system- they can’t be absorbed into the bloodstream. Enzymes break them down into smaller, soluble molecules.