B2 (Cells: membranes & membrane transport, Organelles & Compartmentalization, Cell specialization) Flashcards
Membranes & Membrane Transport.
Diffusion & Osmosis:
Passive transport of substances across membranes.
Membranes & Membrane Transport.
Phospholipid Bilayer:
Forms cell membranes.
Membranes & Membrane Transport.
Active Transport:
Requires energy; against concentration gradient.
Organelles & Compartmentalization.
Nucleus:
Contains genetic material
Organelles & Compartmentalization.
Mitochondria:
Site of cellular respiration. (ATP synthesis)
Organelles & Compartmentalization.
Endoplasmic Reticulum:
Rough (ribosomes)
and
smooth (lipid synthesis).
Cell Specialization.
Tissues:
groups of cells with similar functions.
Cell Specialization.
Organs & Organ Systems:
Combinations of tissues working together.
Cell Specialization.
Stem Cells:
Undifferentiated cells with the potential to become specialized.
Discuss the role of the sodium-potassium pump in maintaining the resting membrane potential of a neuron. Include the ion movements involved.
The sodium-potassium pump goes through cycles of shape changes (to help maintain a negative membrane potential.)
In each cycle, three sodium ions exit the cell, while two potassium ions enter the cell.
These ions travel against the concentration gradient, so this process requires ATP.
Explore the functional significance of the endoplasmic reticulum in protein synthesis. How does the rough endoplasmic reticulum (RER) differ from the smooth endoplasmic reticulum (SER) in terms of function?
SER: creation/ storage of lipids and steroids,
RER: synthesis of various proteins.
The RER is termed “rough” due ribosomal attachments to the surface compared to the SER, which does not have ribosomes
Investigate the ethical considerations surrounding the use of stem cells in medical research and treatment. Highlight potential benefits and challenges.
Ethical considerations:
Source of Stem Cells: Balancing the use of embryonic and adult stem cells.
Therapeutic vs. Reproductive Cloning: Ethical concerns regarding medical vs. reproductive applications.
Informed Consent: Ensuring donors understand implications.
Equitable Access: Avoiding socioeconomic disparities.
Benefits:
Regenerative Medicine: Repairing tissues and organs for degenerative diseases.
Disease Modeling: Studying diseases for targeted treatments.
Drug Testing: Improving drug safety through stem cell testing.
Personalized Medicine: Tailoring treatments based on genetics.
Challenges:
Tumorigenicity: Risk of tumor formation from stem cells.
Immunological Rejection: Addressing host rejection of transplanted cells.
Ethical Concerns: Balancing benefits with ethical considerations.
Unintended Consequences: Understanding long-term effects and unintended outcomes.
Technical Challenges: Overcoming hurdles in controlled stem cell differentiation.
Name the term based off of the definition
Definition: Simultaneous transport of two substances across a membrane using a carrier protein.
Term: Cotransport
What is the function of membrane proteins
Functions: Transport, enzymatic activity, signal transduction, cell adhesion, and recognition.
Totipotent Stem Cells
Definition: Cells with the potential to differentiate into any cell type, including embryonic and extraembryonic cells.
Significance: Early-stage cells in embryonic development.