B influenza A structure

Question 1

genome

Answer 1

is segmented. 8 diff pieces of -ive strand RNA

Question 2

capsid

Answer 2

capsid proteins called NP (nucleocapsid protein). coat each piece of RNA forming a helical capsid. attach to 5’ and 3’ end is P complex

Question 3

3. envelope

Answer 3

contains 2 spike proteins, HA and NA. and the M2 proteins

Question 4

3. hemagglutinin (HA) strucuture

Answer 4

is a trimer. each composed of 2 polypeptides, HA1 is covalently linked to HA2

Question 5

HA1 structure

Answer 5

has a globular head that includes receptor bind site. around the site are epitotes bound by neutralizing antibodies

Question 6

HA2 strucuture

Answer 6

has an internal domain, transmembrane domain, alpha helix and random structure, another alpha helix and fusion peptide

Question 7

Neuraminidase NA strucutre

Answer 7

is a tetramer. each composed of internal domain, transmembrane domain and catalytic site

Question 8

M2 protein is an

Answer 8

ion channel

Question 9

M1 is

Answer 9

the matrix protein. bound to internal domain of HA and NA and lipid bilayer, also bound to viral nucleocapsid