B Cell Development

Question 1

What is the function and types of B cells

Answer 1

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Question 2

Describe the stages of differentiation of B cells

Answer 2

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Question 3

Where is the site of haematopoiesis during gestation

Answer 3

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Question 4

Where is the site of haematopoiesis for B1 B cells

Answer 4

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Question 5

Where is the site of haematopoiesis for B2 B cells

Answer 5

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Question 6

What are the changes in gene rearrangement and cell lineage of B2-B cells

Answer 6

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Question 7

What are characteristics and modifications of the immature B2-B cell

Answer 7

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Question 8

What is the B2-B cell pattern of migration in bone marrow

Answer 8

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Question 9

What are the 2 cell checkpoints in B2-B cell development

Answer 9

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Question 10

What are important cytokines and growth factors for B2-B cell development

Answer 10

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Question 11

What occurs during negative selection of B cells

Answer 11

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Question 12

What occurs during positive selection of B cells

Answer 12

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Question 13

Where do mature B2-B cells migrate after positive selection

Answer 13

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Question 14

What are B1-B cells

Answer 14

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Question 15

What are marginal zone B cells

Answer 15

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Question 16

What is T dependent vs independent B cell activation

Answer 16

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