Axon guidance

Question 1

Pioneer axons can use local cues (_________ cells) on their journey.

Answer 1

guidepost

Question 2

Describe the “growth cone” of an axon.

Answer 2

• It is the specialized tip of a growing axon
• Growth cones have sensory, motor, integrative and adaptive abilities.
• Can continue to grow and navigate correctly when removed from the cell body (for a short period)

Question 3

R_________ and t__________ of selected f_________ leads to axon advance in a particular direction.

Answer 3

Retention; thickening; filopodia