Autopsy Flashcards

1
Q

What are some other terms for an autopsy?

A

Post-mortem examination

Necropsy

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2
Q

What does an autopsy involve?

A

A history

External examination

Internal examination

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3
Q

What is looked at in the external examination?

A

Natural disease

Injury

Medical interventions e.g. surgery

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4
Q

What is looked at in the internal examination?

A

Usually all body systems

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5
Q

What information is gained from the history?

A

Immediate circumstances before death

Previous conditions

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6
Q

What are the additional tests?

A
Histology
Toxicology
Biochemistry
Microbiology
Molecular tests
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7
Q

What is looked at in toxicology?

A

Blood
urine
vitreous
bile

Looking for overdose of therapeutic drugs, recreational drugs

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8
Q

What is looked in biochemistry tests?

A

Measure ketones in blood
Looking for diabetic ketoacidosis, alcoholic ketoacidosis

Urea, creatinine
remain stable after death
so can tell if were elevated at time of death
Looking for renal failure

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9
Q

What is looked at in microbiology?

A

Bacteria, viruses, fungi
Grown in culture
PCR to identify them

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10
Q

What is looked at in molecular tests?

A

Genetic fingerprinting
Identify, eliminate suspects
Test for genetic diseases e.g. cardiomyopathy, conduction disorders

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11
Q

What are the requirements for a coroner’s autopsy?

A

Deceased is unknown

Decreased not seen by doctor within 14 days of dearh

Doctor can’t give cause of death

Unnatural death e.g. murder, accident, suicide

Death related to occupational disease or accident

Death related to medical procedure or treatment

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12
Q

What is a forensic autopsy?

A

Sub-type of coroner’s autopsy

For suspicious deaths

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13
Q

Is consent required for a coronery’s autopsy?

A

No

It’s a legal requirement

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14
Q

What is a consent autopsy?

A

Must get consent from next of kin duh

May limit examination e.g. body parts examined, order in which they are examined

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15
Q

When are paediatric autopsies carried out?

A

Death in utero
Perinatal deaths
Death in infancy, sudden
Suspicious deaths

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16
Q

What is the advantage of post-mortem imaging?

A

Reduces the need for an invasive autopsy

17
Q

When is an autopsy relevant to neuropathology?

A

Death due to trauma to CNS, PNS

neurodegenerative disease