autonomics Flashcards

1
Q

used in bladder atony

A

betanechol

carbachol

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2
Q

act on both M and N receptors

activates m1-m3 receptors in peripheral tissues

A

acetylcholine

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3
Q

miotic in ocular surgery

A

acetylcholine

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4
Q

chlinomimetic used in glaucoma

A

carbachol

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5
Q

acts on m receptors only

A

betanechol

carbachol

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6
Q

m3 selective

A

pilocarpine

cevimeline

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7
Q

used in glaucoma, sjorgen and sicca

A

pilocarpine

cevimeline

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8
Q

triad of sjorgen

A

xerostamia
xerophthalmia
RA

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9
Q

SMOKING CESSATION

A

varenicline

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10
Q

bind to cholinesterase and undergo prompt hydroysis

A

indirect acting cholinomimetics

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11
Q

for diagnosis of MG

A

Edrophonium

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12
Q

diffrentiate cholinergic crisis and myasthenic crisis

A

Edrophonium

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13
Q

only depolarizing neuromuscular blocker

A

succinylcholine

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14
Q

duration of action of Edrophonium

A

5-15 mins

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15
Q

tx of myasthenia gravis

A

neostigmine

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16
Q

for reversal of nondepolarizing NM blockade

A

neostigmine

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17
Q

indirect acting cholimimetic used in glaucoma

A

physostigmine
echothiophate
demecarium

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18
Q

inhibits acetylcholinesterase

A

rivastigmine
galantamine
donepezil
Tacrine

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19
Q

combined with memantine for alzheimer’s

A

Donepezil

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20
Q

NMDA receptor blocker for moderate to severe dementia

A

memantine

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21
Q

signs and symptoms of organophosphate poisoning

A
diarrhea
urination
miosis
bronchospasm
bradycardia
Excitation
Lacrimation
Sweating
Salivation
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22
Q

competetively blocks ALL muscarinic receptors

A

atropine

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23
Q

firstline of tx of OP

A

Atropine

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24
Q

causes hyperthermia

A

atropine

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25
Q

cholinesterase regenerator

A

pralidoxime

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26
Q

se of pralidoxime

A

weakness

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27
Q

prototype of nonselective muscarinic blocker

A

atropine

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28
Q

muscarinic antagonists for parkinsons

A

trihexyphenidyl
BENZtropine
BIPeriden

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29
Q

muscarinic receptor antagonist in ASTHMA AND copd

A

ipratropium

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30
Q

can be used as a monotherapy maintenance for copd

A

glycopyrronium

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31
Q

competetively blocks all muscarinic receptors

antagonize histamine and serotonin

A

scopolamine

32
Q

anti emetic and anti motion sickness

antimuscarinic dx

A

scopolamine

33
Q

applied as transdermal patch

A

scopolamine

34
Q

completely blocks m3 receptors

A

dicyclomine
hyocyamine
glycopyrrolate

35
Q

for IBS, minor diarrhea and decrease acid secretion

A

dicyclomine
hyocyamine
glycopyrrolate

36
Q

slightly blocks m3 receptors

reduce detrussor muscle tone

A

oxybutinin
-FENACIN
trospium
tolteradine

37
Q

used for urge incontinence and post op spasms

A

oxybutinin
-FENACIN
trospium
tolteradine

38
Q

competetively blocks Nn nicotinic Ach receptors

A

hexamethonium
trimethaphan
mecamylamine

39
Q

hypertensive emergencies

A

hexamethonium
trimethaphan
mecamylamine

40
Q

sysnthesis of DOPA from hydroxylation of tyrosine is inhibited by

A

metyrosine

41
Q

vesicular transport of dopamine inhibited by

A

reserpine

42
Q

release of norepinephrine inhibited by

A

guanethidine

43
Q

release of norepinephrine promoted by

A

amphetamines

tyramine

44
Q

diffusion and reuptake of NE inh by

A

cocaine and TCA

45
Q

USED IN NEUROGENIC AND CARDIOGENIC SHOCK AS LAST RESORT

A

norepinephrine

46
Q

used in cardiac arrest, hemostasis

A

epinephrine

47
Q

se of norepinephrine

A

vasospasm
tissue necrosis
infaction
reflex bradycardia

48
Q

beta nonselective sympathomimetic

A

isoproterenol

49
Q

beta nonselective sympathomimetic ofr asthma

A

isoproterenol

50
Q

used as nasal decongestant
drug induced hypotension
orthostatic hypotension

A

phenylephrine

51
Q

se of phenylephrine

A
rebound nasal congestion
supine hypertension
stroke
MI
Urinary retention
52
Q

tx of rebound hypertension

A

phentolamine

53
Q

used for hypertension
cancer pain
opiod withdrawal

A

clonidine

54
Q

for conscious sedation

A

dexmedetomidine

55
Q

selective alpha 2 agonist used as muscle relaxant

A

tizanidine

56
Q

selective alpha 2 agonist for GLAUCOMA

A

Apraclonidine

dec secretion of A.H.

57
Q

SELEctive beta 1 agonist used in acute heart failure and cardiogenic shock

A

dobutamine

58
Q

selective beta 2 agonist for asthma

A

albuterol

salbutamol

59
Q

selective beta 2 agonist for tocolysis

A

terbutaline
ritodrine
isoxuprine

60
Q

se of phenylpropanolamine

A

hemorrhagic stroke

61
Q

irreversibly blocks a adrenergic receptors

A

phenoxybenzamine

62
Q

treatment of pheochromocytoma pre-surgical

A

phenoxybenzamine

63
Q

reversibly block a adrenergic receptors

A

phentolamine

tolazoline

64
Q

antidote to a1 agonist overdose

A

phentolamine

tolazoline

65
Q

cause first dose orthostatic hypotension

A

prasozin

66
Q

most selective for prostatic smooth muscle

A

tamsulosin

67
Q

beta blockers that can be used in pheochromocytoma

A

carvedilol and labetalol

68
Q

masks premonitory symptoms of hypoglycemia from insulin overdosage

A

propanolol

atenolol

69
Q

beta blockers with intrinsic sympathomimetic activity

A

pindolol

acebutolol

70
Q

beta blockers used in glaucoma

A

tomolol

betaxolol

71
Q

beta blocker with longest halflife

A

nadolol

72
Q

betablocker used in SVT

A

Esmolol

73
Q

shortest halflife beta blocker

A

esmolol

74
Q

osmotic agent for glaucoma

A

mannitol

75
Q

cholinomimetic for glaucoma

for ciliary contraction
opening of trabecular meshwork
increased outflow

A

pilocarpine

physostigmine

76
Q

prostaglandin used in glaucoma which increases outflow through canal of Schlemm

A

latanoprost

77
Q

used in glaucome which increase outflow via uveioscleral veins

A

epinephrine