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autonomics Flashcards

1
Q

used in bladder atony

A

betanechol

carbachol

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2
Q

act on both M and N receptors

activates m1-m3 receptors in peripheral tissues

A

acetylcholine

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3
Q

miotic in ocular surgery

A

acetylcholine

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4
Q

chlinomimetic used in glaucoma

A

carbachol

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5
Q

acts on m receptors only

A

betanechol

carbachol

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6
Q

m3 selective

A

pilocarpine

cevimeline

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7
Q

used in glaucoma, sjorgen and sicca

A

pilocarpine

cevimeline

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8
Q

triad of sjorgen

A

xerostamia
xerophthalmia
RA

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9
Q

SMOKING CESSATION

A

varenicline

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10
Q

bind to cholinesterase and undergo prompt hydroysis

A

indirect acting cholinomimetics

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11
Q

for diagnosis of MG

A

Edrophonium

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12
Q

diffrentiate cholinergic crisis and myasthenic crisis

A

Edrophonium

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13
Q

only depolarizing neuromuscular blocker

A

succinylcholine

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14
Q

duration of action of Edrophonium

A

5-15 mins

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15
Q

tx of myasthenia gravis

A

neostigmine

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16
Q

for reversal of nondepolarizing NM blockade

A

neostigmine

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17
Q

indirect acting cholimimetic used in glaucoma

A

physostigmine
echothiophate
demecarium

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18
Q

inhibits acetylcholinesterase

A

rivastigmine
galantamine
donepezil
Tacrine

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19
Q

combined with memantine for alzheimer’s

A

Donepezil

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20
Q

NMDA receptor blocker for moderate to severe dementia

A

memantine

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21
Q

signs and symptoms of organophosphate poisoning

A 
diarrhea
urination
miosis
bronchospasm
bradycardia
Excitation
Lacrimation
Sweating
Salivation
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22
Q

competetively blocks ALL muscarinic receptors

A

atropine

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23
Q

firstline of tx of OP

A

Atropine

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24
Q

causes hyperthermia

A

atropine

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25
cholinesterase regenerator
pralidoxime
26
se of pralidoxime
weakness
27
prototype of nonselective muscarinic blocker
atropine
28
muscarinic antagonists for parkinsons
trihexyphenidyl BENZtropine BIPeriden
29
muscarinic receptor antagonist in ASTHMA AND copd
ipratropium
30
can be used as a monotherapy maintenance for copd
glycopyrronium
31
competetively blocks all muscarinic receptors | antagonize histamine and serotonin
scopolamine
32
anti emetic and anti motion sickness | antimuscarinic dx
scopolamine
33
applied as transdermal patch
scopolamine
34
completely blocks m3 receptors
dicyclomine hyocyamine glycopyrrolate
35
for IBS, minor diarrhea and decrease acid secretion
dicyclomine hyocyamine glycopyrrolate
36
slightly blocks m3 receptors | reduce detrussor muscle tone
oxybutinin -FENACIN trospium tolteradine
37
used for urge incontinence and post op spasms
oxybutinin -FENACIN trospium tolteradine
38
competetively blocks Nn nicotinic Ach receptors
hexamethonium trimethaphan mecamylamine
39
hypertensive emergencies
hexamethonium trimethaphan mecamylamine
40
sysnthesis of DOPA from hydroxylation of tyrosine is inhibited by
metyrosine
41
vesicular transport of dopamine inhibited by
reserpine
42
release of norepinephrine inhibited by
guanethidine
43
release of norepinephrine promoted by
amphetamines | tyramine
44
diffusion and reuptake of NE inh by
cocaine and TCA
45
USED IN NEUROGENIC AND CARDIOGENIC SHOCK AS LAST RESORT
norepinephrine
46
used in cardiac arrest, hemostasis
epinephrine
47
se of norepinephrine
vasospasm tissue necrosis infaction reflex bradycardia
48
beta nonselective sympathomimetic
isoproterenol
49
beta nonselective sympathomimetic ofr asthma
isoproterenol
50
used as nasal decongestant drug induced hypotension orthostatic hypotension
phenylephrine
51
se of phenylephrine
``` rebound nasal congestion supine hypertension stroke MI Urinary retention ```
52
tx of rebound hypertension
phentolamine
53
used for hypertension cancer pain opiod withdrawal
clonidine
54
for conscious sedation
dexmedetomidine
55
selective alpha 2 agonist used as muscle relaxant
tizanidine
56
selective alpha 2 agonist for GLAUCOMA
Apraclonidine | dec secretion of A.H.
57
SELEctive beta 1 agonist used in acute heart failure and cardiogenic shock
dobutamine
58
selective beta 2 agonist for asthma
albuterol | salbutamol
59
selective beta 2 agonist for tocolysis
terbutaline ritodrine isoxuprine
60
se of phenylpropanolamine
hemorrhagic stroke
61
irreversibly blocks a adrenergic receptors
phenoxybenzamine
62
treatment of pheochromocytoma pre-surgical
phenoxybenzamine
63
reversibly block a adrenergic receptors
phentolamine | tolazoline
64
antidote to a1 agonist overdose
phentolamine | tolazoline
65
cause first dose orthostatic hypotension
prasozin
66
most selective for prostatic smooth muscle
tamsulosin
67
beta blockers that can be used in pheochromocytoma
carvedilol and labetalol
68
masks premonitory symptoms of hypoglycemia from insulin overdosage
propanolol | atenolol
69
beta blockers with intrinsic sympathomimetic activity
pindolol | acebutolol
70
beta blockers used in glaucoma
tomolol | betaxolol
71
beta blocker with longest halflife
nadolol
72
betablocker used in SVT
Esmolol
73
shortest halflife beta blocker
esmolol
74
osmotic agent for glaucoma
mannitol
75
cholinomimetic for glaucoma for ciliary contraction opening of trabecular meshwork increased outflow
pilocarpine | physostigmine
76
prostaglandin used in glaucoma which increases outflow through canal of Schlemm
latanoprost
77
used in glaucome which increase outflow via uveioscleral veins
epinephrine

Pharma Autonomics (4 decks)

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