Autonomic receptors Flashcards

1
Q

Alpha 1

A

Gq
Increase vascular smooth muscle contraction
Increase pupillary dilator muscle contraction (Mydriasis)
Increase intestinal and bladder sphincter muscle contraction

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2
Q

Alpha 2

A
Gi
Decrease sympathetic outflow (in CNS)
Decrease insulin release
Decrease lipolysis
Decrease aqueous humor production
Increase platelet aggregation
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3
Q

Beta 1

A
Gs
Increase heart rate
Increase contractility
Increase renin release
Increase lipolysis
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4
Q

Beta 2

A
Gs
Vasodilation
Bronchodilation
Increase lipolysis
Increase insulin release
Increase aqueous humor production
Decrease uterine tone
Ciliary muscle relaxation
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5
Q

Beta 3

A

Gs
Increase Lipolysis
Increase thermogenesis in skeletal muscle

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6
Q

M1

A

Gq
CNS
Enteric nervous system

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7
Q

M2

A

Gi
Decrease heart rate
Decrease contractility of atria

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8
Q

M3

A

Gq
Increase exocrine gland secretions (lacrimal, sweat, salivary, gastric acid)
Increase gut peristalsis
Increase bladder contraction
Bronchoconstriction
Increase pupillary sphincter muscle contraction (Miosis)
Ciliary muscle contraction (accommodation)

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9
Q

D1

A

Gs

Relaxes renal vascular smooth muscle

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10
Q

D2

A

Gi

Modulates transmitter release (esp. in brain)

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11
Q

H1

A
Gq
Increase nasal and bronchial mucus production
Increase vascular permeability
Contraction of bronchioles
Pruritus
Pain
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12
Q

H2

A

Gs

Increase gastric acid secretion

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13
Q

V1

A

Gq

Increase vascular smooth muscle contraction

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14
Q

V2

A

Gs

Increase H20 permeability and reabsorption in collecting tubules of kidney

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