Autonomic Nervous System Drugs Flashcards
1
Q
AUTONOMIC DRUGS
A
- Autonomic drugs have been defined as those that exhibit pharmacological effects that mimic the activation, intensification, or inhibition of either the sympathetic or parasympathetic nervous system.
2
Q
PHARMACOLOGIC EFFECT OF ANS DRUGS
A
- When autonomic medications are administered, the aim is to treat target organ diseases via autonomic nerves rather than treat an autonomic disorder.
3
Q
ADVERSE REACTIONS
A
D - Diarrhea
U - Urination
M – Miosis and Muscle Weakness
B - Bronchorrhea
B - Bradycardia
E - Emesis
L - Lacrimation
S – Salivation/ Sweating
4
Q
ADVERSE EFFECTS
A
A – Agitation
B – Blurred vision
C- Constipation, Confusion
D –Dry mouth
S – Stasis of urine and Sweating
5
Q
ADRENERGIC AGONIST
A
- Also known as Sympathomimetics, only works on the Sympathetic Nervous System (SNS) where it stimulates the SNS and they mimic the effect of Norepinephrine(NE).
6
Q
CATEGORY BASED ON CHEMICAL STRUCTURE
A
- Catecholamines- it has catechol rings and amines, it is also usually given parenterally.
- Noncatecholamines- it has no catechol ring, and most noncatecholamines are effective orally.
7
Q
EPINEPHRINE
A
- Adrenaline, is secreted by the adrenal medulla & a neuroeffector transmitter of adrenergic drugs. Its Pharmacologic Class is Adrenergic, Therapeutic Class is Vasopressor(constricts blood vessels). Its receptors are A1, A2, B1, & B2.
8
Q
ADRENERGIC ANTAGONIST
A
- Also known as Sympatholytics, only works on the Sympathetic Nervous System(SNS), where it inhibits the SNS and blocks the effects of SNS.
9
Q
ALPHA 1
A
- It is a receptor that is used for Hypotension, Nasal Congestion, and Dilation of Pupils
10
Q
ALPHA 2
A
- It is a receptor that is used for Hypertension
11
Q
BETA 1
A
- It is a receptor that is used for Heart Failure, Cardiac Arrest, and Shock
12
Q
BETA 2
A
- It is a receptor that is used for Asthma, and Premature labor of contraction
13
Q
ALPHA BLOCKERS
A
Causes:
- Relaxation of smooth muscles
- Vasodilation: hypertension and PVDs
- Reduces contraction of smooth muscle in bladder and prostate
Includes:
- Terazosin
- Doxazosin
- Prazosin
14
Q
BETA BLOCKERS
A
- Decrease heart rate
- Decreases blood pressure
- Useful for treating mild to moderate hypertension, angina pectoris, and myocardial infarction
Includes:- Atenolol
- Propranolol
- Pindolol
- Timolol
- Metoprolol
15
Q
CHOLINERGIC AGONISTS
A
- Also known as Parasympathomimetic, only works on the Parasympathetic Nervous System (PNS) where it stimulates the PNS and they mimic the effect of Acetylcholine.