Autonomic Nervous System Drugs

Question 1

List the effects of Alpha 1 Adrenergic receptors.

Answer 1

Eye - pupil dilation
Blood vessels - vasoconstriction (increased BP)
Bladder - bladder relaxes (less pressure = less need to pee); constriction of bladder sphincter

Question 2

Influences one type of receptor

Answer 2

SELECTIVE

Question 3

Influences all receptors

Answer 3

NON-SELECTIVE

Question 4

Sends impulses to the CNS

Answer 4

AFFERENT

Question 5

Receives impulses, transmits through the spinal cord to effector organ cells

Answer 5

EFFERENT

Question 6

List the effects of Beta 1 Adrenergic receptors.

Answer 6

Heart - increased heart rate to pump more blood, increased conduction through AV node, increased force of contraction
Kidney - secretes renin to retain water

Question 7

What are the other names for Adrenergic drugs?

Answer 7

Adrenergic agonists & Sympathomimetics (because they mimic the SNS)

Question 8

What are Beta-Adrenergic Adverse Effects?

Answer 8

CNS - tremors, headaches, nervousness, dizziness
Cardiovascular - Palpitations, tachycardia, dysrhythmia, angina
Other - sweating, nausea, vomiting, muscle cramps

Question 9

WHAT ARE THE ADVERSE EFFECTS

Answer 9

A –Agitation
B –Blurred vision
C-Constipation, Confusion
D –Dry mouth
S –Stasis of urine and Sweating

Question 10

ADVERSE SIDE EFFECTS

Answer 10

-Prolong Apnea
-Hyperkalemia
-Malignant Hyperthermia

Question 11

ADVERSE REACTIONS

Answer 11

D -Diarrhea
U -Urination
M –Miosis and Muscle Weakness
B -Bronchorrhea
B -Bradycardia
E -Emesis
L -Lacrimation
S –Salivation/ Sweating

Question 12

List the effects of Beta 2 Adrenergic receptors.

Answer 12

Smooth muscle of lungs - bronchodilation

Question 13

Drugs that produces a response

Answer 13

Agonist

Question 14

Drugs that blocks a response

Answer 14

Antagonist

Question 15

Has a catechol ring and amines

Answer 15

CATECHOLAMINES

Question 16

SIDE EFFECTS OF ADRENERGIC AGONISTS

Answer 16

Headache.
Tremor.
Irritation/burning in the eye.
Blurred vision.
Hypertension.
Tachycardia (irregular heartbeat)
Palpitation.
Dry mouth

Question 17

Blocking the transmission at the sympathetic and parasympathetic ganglia in the autonomic nervous system

Answer 17

GANGLIONIC BLOCKERS

Question 18

Effects of Beta-blockers (atenolol/metoprolol) and adverse effects.

Answer 18

-Decreased demand for myocardial oxygen (decreased angina).
-Decreased heart rate.
-Decreased force of contraction (lowers hypertension).

Question 19

When Autonomic drugs are given, the goal is not to treat an autonomic disorder, it is to correct disorders of target organs through autonomic nerves

Answer 19

PHARMACOLOGIC EFFECT

Question 20

What are Alpha 1 Adrenergic Adverse Effects?

Answer 20

dizziness, headache, palpitations, fluid retention, drowsiness, weakness, priapism, thrombocytopenia and atrial fibrillation;