Autonomic Nervous System Flashcards
Two division of the Motor Nervous System:
- Somatic Nervous system
- Autonomic Nervous system
How is ANS linked to target tissue?
Two neural pathway:
- pre-ganglionic neuron in: CNS
- Post-ganglionic neuron in: Autonomic Ganglion
- Neuroeffector Junction in: Peripheral Tissue
Division of the Autonomic Nervous System:
Sympathetic: fight or flight
Parasympathetic: rest & digest
Sympathetic Nervous system Functions:
- preps body to fight or escape
- preps body for esoteric activities i.e. exercise
- involved in behavioral responses e.g. stress & fear
Consequences of Increased Activity of Sympathetic Division:
- ^ heart rate
- ^ blood pressure/stroke volume
- dilation of pupils, airways, & blood vessels to muscles
- contraction of urogenital sphincters
- decreased motility of digestive tract
- reproductive system attenuated
collectively: ^ BSL, enhance delivery of oxygenated blood to muscle, & potentiate visual awareness
Parasympathetic Nervous System Functions:
- preps other systems of body for rest
facilitates relaxation & recuperation - restores metabolic energy stores & enables rest & recovery
Consequences of Increased Activity of Sympathetic Division:
- decreased heart rate
- constriction of pupils
- increased motility & secretion of digestive enzymes in digestive tract
- decrease in metabolic rate
- relaxation of urogenital sphincters/ stimulation of defecation & urination
Sympathetic Pre-ganglionic Neurons:
- cell body: lateral horns of upper spinal cord
- small diameter myelinated axon leaves spinal cord via ventral roots
- synapses with post ganglionic neurons in sympathetic chain ganglia or collateral ganglia
- short neurons
Sympathetic Post-ganglionic Neurons:
- cell bodes in either sympathetic chain ganglia or collateral ganglia
- small diameter eliminated axons & axon terminal in peripheral nerves
- comparative long(compared to pre-ganglionic neurons of sympathetic division)
Parasympathetic Pre-Ganglionic Neurons:
- cell bodies in brain stem or lateral horns
- unmeylinated axons leave brain stem via cranial nerves or spinal cord via ventral roots
- synapse with post-ganglionic neurons in terminal ganglia in/ close to peripheral tissue they innervate
- long neurons
Parasympathetic Post-ganglionic Neurons:
- cell bodies in termianl ganglia or peripheral tissue
- short, small diameter myelinated or unmyelinated axons in peripheral nerves
- short neurons
Sympathetic: Neurotransmitter & receptor of Pre-Ganglionic Neurons:
- releases neurotransitter (ACh)
- ACh binds to nicotinic acetylcholine receptor (ionotropic receptor)
- causes excitation of post-ganglionic
- depolarizes post-synaptic membrane by opening a cation non-selective channel
- ESPS large enough to cause AP in Post-G
- excites Post-G neurons
Sympathetic: Neurotransmitter & receptor of Post-Ganglionic Neurons:
- releases nor-adrenaline as neurotransmitter
- receptors (adrenergic receptors) located in plasma membrane innervated by post-G neurons
Parasympathetic: Neurotransmitter & receptor of Pre-Ganglionic Neurons:
- releases ACh as neurotransmitter
- ACh binds to nicotinic acetylcholine receptors (ioniotropic receptor)
- depolarizes post-synaptic membrane by opening cation non-selective ion channel
- ESPS large enough to cause AP in Post-G
- excites Post-G neurons
Sympathetic: Neurotransmitter & receptor of Post-Ganglionic Neurons:
- releases acetylcholine as neurotransmitter
- binds to muscarinic acetylcholine receptors
- metabolic receptors
- mediate their effect by an intra-cellular second messenger