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PLE 2017: Pharmacology > Autonomic Drugs > Flashcards

Autonomic Drugs Flashcards

1
Q 
Muscarinic Agonist (M1, M2, M3)
U: Bowel and bladder atony
A

Betanechol

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2
Q

Muscarinic and Nicotinic Agonist

U: Cataracts

A

Carbachol

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3
Q 
Muscarinic Agonist (M3)
U: Sjogren Syndrome, Sicca Syndrome
A

Pilocarpine

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4
Q

Nicotinic Agonist

U: Smoking cessation

A

Varenicline

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5
Q

Acetylcholinesterase Inhibitor

U: Tensilon Test

A

Edrophonium

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6
Q

Acetycholinesterase Inhibitor
DOC: Myasthenia Gravis
U: Reversal of Muscle Relaxants; Ogilvie Syndrome

A

Neostigmine

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7
Q

Acetylcholinesterase Inhibitor

U: Alzheimer’s Disease

A

Rivastigmine

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8
Q

Non-selective Muscarinic Antagonist

Hyoscine-N-Butyl-Bromide

A

Scopolamine

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9
Q

Non-selective Muscarinic Antagonist
DOC: Organophosphate Toxicity
SE: Hyperthermia

A

Atropine

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10
Q

Non-selective Muscarinic Antagonist

Shortest DOA

A

Tropicamide

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11
Q

Non-selective Muscarinic Antagonist

U: Bronchial Asthma

A

Ipratropium, Tiotropium

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12
Q

Non-selective Muscarinic Antagonist

U: Urinary incontinence and urgency

A

Oxybutinin

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13
Q

Chemical antagonist of Organophosphates

Given within 6-8 hours post-exposure

A

Pralidoxime

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14
Q

Sympatomimetic (A1, B1, B2)

DOC: Anaphylaxis

A

Epinephrine

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15
Q

Sympatomimetic (A1, B1, B2)

Effect: Alpha > Beta

A

Norepinephrine

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16
Q

Sympatomimetic (A1, B1, D1)

A

Dopamine

17
Q

Non-selective Beta Agonist

U: Bronchial Asthma

A

Isoproterenol

18
Q

A1 Agonist
U: Decongestant
SE: Rhinitis Medicamentosa

A

Phenylephrine

19
Q

A2 Agonist

SE: Rebound Hypertension

A

Clonidine

20
Q

A2 Agonist
U: Pre-ecclampsia
SE: Hemolytic Anemia

A

Methyldopa

21
Q

A2 Agonist

U: Glaucoma

A

Apraclonidine

Brimonidine

22
Q

B1 Agonist

U: Cardiogenic Shock

A

Dobutamine

23
Q

B2 Agonist

DOC: Bronchial Asthma (Acute)

A

Salbutamol

24
Q

D1 Agonist

U: Hypertension

A

Fenoldopam

25
Q

D2 Agonist

U: Hyperprolactinemia, Parkinson’s Disease

A

Bromocriptine

26
Q

Non-selective Alpha Antagonist
Irreversible
U: Pheochromocytoma

A

Phenoxybenzamine

27
Q

Non-selective Alpha Antagonist
Reversible
U: Rebound HPN, Pheochromocytoma

A

Phentolamine

28
Q

A1 Antagonist

U: Co-existing HPN and BPH

A

Prazosin
Doxazosin
Terazosin

29
Q

A1a Antagonist

Prostate-selective

A

Tamsulosin

30
Q

Non-selective Beta Antagonist
A1 Antagonist
U: Pheochromocytoma
Safe for pregnancy

A

Labetalol

31
Q

Non-selective Beta Antagonist
A1 Antagonist
U: Pheochromocytoma
Reduces mortality in HF

A

Carvedilol

32
Q

Non-selective Beta Antagonist

Longest half-life

A

Nadolol

33
Q

Selective Beta Antagonist
Shortest half-life
U: SVT, Thyroid Storm

A

Esmolol

34
Q

Beta Antagonists

Intrinsic Sympatomimetic Activity

A

Pindolol (Non-selective)

Acebutolol (Selective)

35
Q

Beta Antagonists

No local anesthetic effects

A

Timolol (Non-selective)

Betaxolol (Selective)

36
Q

Selective Beta Antagonist

Vasodilatory effect

A

Nebivolol

37
Q

B2 Agonist

U: Tocolytic

A

Terbutaline

38
Q

Non-selective Muscarinic Antagonist

U: Parkinson’s Disease

A

Benztropine
Biperiden
Trihexyphenidyl

PLE 2017: Pharmacology (1 decks)

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