Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MS1 - CPR > Autonomic Drugs > Flashcards

Autonomic Drugs Flashcards

1
Q

Treatment for neurogenic orthorstatic hypotension.

A

Pyridostigmine (AChE inhibitor)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Name the drugs that can cause bronchoconstriction as an AE. Name their mechanisms of action.

A

1 and 2. Carvedilol and labetalol: a1 and beta antagonists.

  1. Metropolol: B1 antagonist but can bind to B2 also.
  2. Propranolol: non-selective beta blocker.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Treats performance anxiety.

A

Propranolol (non-selective B blocker)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Extravasation necrosis SAE.

A

Norepinephrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is alpha-methyldopa converted to?

A

alpha-methylnorephrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Treatment for shock.

A

Dopamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Treats gestational hypertension.

A

a-methyldopa (a2 agonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which drugs cause orthostatic hypotension as a SAE?

A
  1. Clonidine (centrally-acting a2 agonist)
  2. a-methyldopa (centrally-acting a2 agonist)
  3. Doxazosin (a1 antagonist)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which drug is used for reversal of vagal bradycardia?

A

Atropine (non-selective muscarinic antagonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which drugs cause “local necrosis” as a SAE?

A

Dopamine and epinephrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is an antidote for cholinesterase inhibitor toxicity?

A

Atropine (non-selective muscarinic antagonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Name the mechanism of action and corresponding physiologic response of drug binding:

Phenoxybenzamine

A

Irreversible a1 and a2 receptor antagonist

Vasodilation and increased epi and norepi release –> increased HR and contractility (B1) and skeletal muscle vasodilation (B2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Name the mechanism of action:

Isoproterenol

A

Non-selective beta agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What does stimulation of B2 receptors do?

A

Dilation of skeletal muscle vasculature and dilation of bronchiolar smooth muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Name the mechanism of action:

Phentolamine

What other drug that we know has this same mechanism of action?

A

Non-selective alpha antagonist

Phenoxybenzamine is also a non-selective alpha antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Name the mechanism of action:

a-methyldopa

What other drug that we know has this same mechanism of action?

A

a2 agonist

clonidine is also an a2 agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Name the mechanism of action and corresponding physiologic response of drug binding:

Darifenacin

A

M3 blocker

stops smooth muscle contraction in bladder and glands - used for overactive bladder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

In what organ are dopaminergic receptors found and what happens when they bind dopamine?

A

Found in the kidneys; binding increases renal blood flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Describe alpha and beta receptor affinity for norepinephrine.

A

a1 > a2 > B1 > B2

20
Q

Describe alpha and beta receptor affinity for epinephrine (low doses).

A

B2 > B1 > a1 > a2

21
Q

Name the mechanism of action:

Doxazosin

What other drug has the same mechanism of action?

A

a1 antagonist

prazosin as well (anything that ends with -osin is an a1 antagonist)

22
Q

Name the mechanism of action:

Midodrine

A

a1 agonist

23
Q

Name the mechanism of action:

Dobutamine

A

B1 agonist

24
Q

Name the mechanism of action:

Phenylephrine

A

alpha agonist

25
Q

Name the mechanism of action:

Pyridostigmine

A

Acetylcholinesterase inhibitor

26
Q

Name the mechanism of action:

Phenoxybenzamine

A

Covalent (long lasting) alpha antagonist

27
Q

Name the mechanism of action:

Phentolamine

A

alpha antagonist

28
Q

Name the SAEs for:

Pyridostigmine

A

Respiratory depression, bradycardia, lacrimation, diarrhea

29
Q

Name the SAEs for:

Atropine

A

Tachycardia

30
Q

Name the SAEs for:

Clonidine

A

Postural hypotension, bradycardia, sedation, dry mouth

31
Q

Name the SAEs for:

Dobutamine

A

Tachycardia

32
Q

Name the SAEs for:

Dopamine

A

Tachycardia, vasoconstriction, local necrosis

33
Q

Name the SAEs for:

Epinephrine

A

Arrhythmia, local necrosis

34
Q

Name the SAEs for:

Isoproterenol

A

Tachycardia, hypotension

35
Q

Name the SAEs for:

methyldopa

A

Postural hypotension, bradycardia, sedation, dry mouth

36
Q

Name the SAEs for:

Midodrine

A

Hypertension, bradycardia

37
Q

Name the SAEs for:

Norepinephrine

A

Arrhythmia, extravasation necrosis

38
Q

Name the SAEs for:

Phenylephrine

A

Hypertension, bradycardia

39
Q

Name the SAEs for:

Carvedilol

A

Bradycardia, bronchoconstriction

40
Q

Name the SAEs for:

Doxazosin

A

Orthostatic hypotension

41
Q

Name the SAEs for:

Labetalol

A

Bradycardia, bronchoconstriction

42
Q

Name the SAEs for:

Metoprolol

A

Bradycardia, bronchoconstriction

43
Q

Name the SAEs for:

Phentolamine

A

Orthostatic hypotension, tachycardia, nasal congestion

44
Q

Name the SAEs for:

Phenoxybenzamine

A

Orthostatic hypotension, tachycardia, nasal congestion

45
Q

Name the SAEs for:

Propranolol

A

Bradycardia, bronchoconstriction

MS1 - CPR (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions