Autoimmunity Flashcards
1
Q
What fluorescent antibody tests are positive in autoimmune chronic active hepatitis?
A
ANA, Anti-smooth muscle (ASMA)
2
Q
What is high and low in Hashimoto’s and what antibodies should be found?
A
High TSH, low T4/thyroxine; should be antithyroglobulin, and antithyroid peroxidase
3
Q
What antibodies are associated with Pernicious anemia>
A
anti-intrinsic factor, anti-parietal cell
4
Q
In >90% of cases of primary biliary cirrhosis,/ cholangitis these autoantibodies are found?
A
anti-mitochondrial
5
Q
common antibodies found in Scleroderma/PSS/CREST
A
anti-centromere, anti-nucleolar, Scl-70
6
Q
SLE hallmark antibody:
A
anti-dsDNA in ANA; may see anti-Sm in 20%
7
Q
specific antibodies for Sjogren’s
A
anti-SS-A (Ro) and anti-SS-B (La)
