autoimmune markers Flashcards

1
Q

rheumatoid factor

A

first line for RA

70% positive, if negative test for anti-CCP

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2
Q

anti-ccp

A

Rheumatoid arthritis

much higher specificity than RhF

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3
Q

dsDNA

A

SLE (99% specifcity)

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4
Q

anti-histone antibody

A

drug induced SLE

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5
Q

smith antibody

A

SLE (rarely used)

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6
Q

Ro/La

A

sjogrens syndrome

neonatal SLE

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7
Q

anticardiolipin

A

APLS

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8
Q

lupus anticoagulant

A

APLS

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9
Q

pANCA

A

EPGA

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10
Q

cANCA

A

GPA

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11
Q

Scl70

A

systemic sclerosis

scleroderma

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12
Q

Jo1

A

polymyositis

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13
Q

anti-centromere

A

limited systemic sclerosis

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14
Q

temporal arteritis

A

CRP / ESR

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15
Q

polymyalgia rheumatica

A

CRP / ESR

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16
Q

creatinine kinase

A

polymyositis

NORMAL in polymyalgia rheumatica