Autoimmune Diseases To Know Flashcards
AGN (acute glomerulonephritis)
Targets streptococcal Ags
Type III
Kidneys
SLE (systemic lupus erythematosis)
Targets DNA
Type III
Multiorgan (always kidneys)
Rheumatic fever
Targets strep Ags
Heart
Rheumatoid arthritis
IgM anti-IgG (joints with symmetric arthritis)
Type III
Multiple sclerosis
Targets nerve Ags
Paralysis
Ankylosis spondylitis
HLA B-27
Arthritis involving spine
Reiter’s syndrome
Targets HLA B-27
Arthritis, urethritis, conjunctivitis
Psoriasis
Targets skin ag or group A strep in guttate psoriasis
Hemolytic anemia
Targets RBC Ags
Immune thrombocytopenic purpura
Targets platelet ags
Type I diabetes
Targets beta cells
Hashimoto’s thyroiditis
Targets T3 and T4
Hypothyroidism
Grave’s disease
Targets TSH receptor
Hyperthyroidism
Inflammatory bowel disease
Targets gut microbes
Crohns and ulcerative colitis
Myasthenia gravis
Targets nicotinic ach receptor
Muscle weakness