Autoimmune Disease

Question 1

Autoimmune Disease

Answer 1

Autoantibodies and T cells are unable to recognize own cells and will launch attack on own cells.
May be due to overabundance or overactive of helper T lymphocytes

Question 2

Factors for autoimmune disease

Answer 2

Environment
Immune regulation
Genes

Question 3

2 Types of autoimmune disease

Answer 3

Organ specific & Non organ specific

Brain, Thyroid, Stomach
Skin, muscle, kidney, joints

Question 4

Systemic lupus erythematosus (SLE)

Answer 4

Ur immune system attack ur own cells

Question 5

Single organ autoimmune disease

Answer 5

Hemolytic anemia (blood cells)
Graves' disease and type I diabetes mellitus (endocrine glands)
Multiple sclerosis (nervous tissue)

Question 6

Hemolytic anemia affect where? Consequences?

Answer 6

RBC, anemia with fatigue , weakness , lightheadedness and enlarged spleen. Anemia can be severe or fatal.

Question 7

Graves’ disease affect where? Consequences?

Answer 7

Thyroid gland. High levels of thyroid hormones. (hyperthroidism) Body produce antibodies to receptor for thyroid stimulating hormone (TSH).

Question 8

Type 1 diabetes mellitus affect where? Consequences?

Answer 8

Beta cells of pancreas (insulin). Beta cells destroyed, lack of insulin. Cells in pancreas destroyed

Question 9

Rheumatoid Arthritis

Answer 9

Inflammation of synovial lining of joint and cartilage destruction. IgM bind to patients own IgG which can activate complement system (cell destruction)

Question 10

Immunodeficiency 2 types

Answer 10

Primary - Inherited / genetic

Secondary - Acquired

Question 11

Immunodeficiency

Answer 11

Loss of cell type, function and numbers