Autoimmune Flashcards
Thymus immune function
Formation of T cells
Tonsils/Adenoids function
Distinguish invaders for destruction
Spleen function
Filters blood and distributes T and B cells
Lymph gland function
Storage and WBC formation
Bone marrow immune function
B cells are produced in bone marrow
Explain the inflammatory process
Break in tissue barrier –> release histamine –> blood flow to the area increases, capillaries leak –> allows phagocytes, platelets… to reach the site –> phagocytes eat germs, dead cells… platelets stop blood flow at injury site
Innate immunity
Local, generalized response
Adaptive immunity
Traveling immune response that recognizes specific invaders
Breakdown of the inflammatory response
- Bacteria and pathogens enter wounds
- platelets are released
- Mast cells mediate vasodilation. Paramedics of the group. Delivery of blood, plasma, and cells to area increases
- Neutrophils secrete factors that kill and degrade pathogens
- Neutrophils and macrophages remove pathogens by phagocytosis
- Macrophages secrete hormones and cytokines that attract immune system cells to the cite and activate cells involved in tissue repair
- Inflammatory response continues until foreign material is eliminated and wound is repaired
Symptoms of autoimmune disorders
- fatigue, fever, general malaise
- itchy skin, wt changes, muscle aches, stiff joints, diarrhea, numbness/tingling, blurry vision, SOB, mouth sores, rashes, reproductive issues, memory problems..
Which gender is more susceptible to autoimmune disorders?
Women
Autoimmune disorders are most common in which part of the world
Industrialized nations